The retromer complex safeguards against neural progenitor-derived tumorigenesis by regulating Notch receptor trafficking

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The retromer complex safeguards against neural progenitor-derived tumorigenesis by regulating Notch receptor trafficking

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http://www.wikidata.org/entity/Q58764547

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im September 2018 veröffentlichter wissenschaftlicher Artikel

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scientific article published on 04 September 2018

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wetenschappelijk artikel

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наукова стаття, опублікована у вересні 2018

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The retromer complex safeguard ...... ing Notch receptor trafficking

@en

The retromer complex safeguard ...... ing Notch receptor trafficking

@nl

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Item

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The retromer complex safeguard ...... ing Notch receptor trafficking

@en

The retromer complex safeguard ...... ing Notch receptor trafficking

@nl

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The retromer complex safeguard ...... ing Notch receptor trafficking

@en

The retromer complex safeguard ...... ing Notch receptor trafficking

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P1476

The retromer complex safeguard ...... ing Notch receptor trafficking

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P2093

Bo Li

http://www.w3.org/2001/XMLSchema#string

Chouin Wong

http://www.w3.org/2001/XMLSchema#string

Rongbo Sun

http://www.w3.org/2001/XMLSchema#string

Rulan Zhang

http://www.w3.org/2001/XMLSchema#string

Shihong Max Gao

http://www.w3.org/2001/XMLSchema#string

Yulong Li

http://www.w3.org/2001/XMLSchema#string

P2860

Recognition and ubiquitination of Notch by Itch, a hect-type E3 ubiquitin ligase

VARP is recruited on to endosomes by direct interaction with retromer, where together they function in export to the cell surface

SNX27 mediates retromer tubule entry and endosome-to-plasma membrane trafficking of signalling receptors.

The retromer complex influences Wnt secretion by recycling wntless from endosomes to the trans-Golgi network

Wingless secretion requires endosome-to-Golgi retrieval of Wntless/Evi/Sprinter by the retromer complex

A SNX3-dependent retromer pathway mediates retrograde transport of the Wnt sorting receptor Wntless and is required for Wnt secretion

Control of the activity of WW-HECT domain E3 ubiquitin ligases by NDFIP proteins

Loss of negative regulation by Numb over Notch is relevant to human breast carcinogenesis

The retromer complex in development and disease

The retromer complex is required for rhodopsin recycling and its loss leads to photoreceptor degeneration

P31

scholarly article

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10.7554/ELIFE.38181

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English

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http://www.w3.org/2001/XMLSchema#string

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Yan Song

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2018-09-04T00:00:00Z

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30176986

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6140715

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