Isoxazolopyrimidine-Based Inhibitors of Dihydroorotate Dehydrogenase with Antimalarial Activity

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Isoxazolopyrimidine-Based Inhibitors of Dihydroorotate Dehydrogenase with Antimalarial Activity

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wetenschappelijk artikel

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наукова стаття, опублікована в серпні 2018

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Isoxazolopyrimidine-Based Inhi ...... ase with Antimalarial Activity

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Isoxazolopyrimidine-Based Inhi ...... ase with Antimalarial Activity

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Isoxazolopyrimidine-Based Inhi ...... ase with Antimalarial Activity

@en

Isoxazolopyrimidine-Based Inhi ...... ase with Antimalarial Activity

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Isoxazolopyrimidine-Based Inhi ...... ase with Antimalarial Activity

@en

Isoxazolopyrimidine-Based Inhi ...... ase with Antimalarial Activity

@nl

P1476

Isoxazolopyrimidine-Based Inhi ...... ase with Antimalarial Activity

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P2093

Adolfo Garcia-Pérez

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David M Shackleford

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David Waterson

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Farah El Mazouni

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Francisco Javier Gamo

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Jayan T Joseph

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John White

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Jorge Fernandez

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Karen L White

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Krishne Manjalanagara

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P2860

Artemisinin Resistance in Plasmodium falciparum Malaria

Evidence of Artemisinin-Resistant Malaria in Western Cambodia

Thousands of chemical starting points for antimalarial lead identification

Improved murine model of malaria using Plasmodium falciparum competent strains and non-myelodepleted NOD-scid IL2Rgammanull mice engrafted with human erythrocytes

Designing the next generation of medicines for malaria control and eradication

A long-duration dihydroorotate dehydrogenase inhibitor (DSM265) for prevention and treatment of malaria

Structural Plasticity of Malaria Dihydroorotate Dehydrogenase Allows Selective Binding of Diverse Chemical Scaffolds

Novel Inhibitors of Plasmodium falciparum Dihydroorotate Dehydrogenase with Anti-malarial Activity in the Mouse Model

Structure-Guided Lead Optimization of Triazolopyrimidine-Ring Substituents Identifies Potent Plasmodium falciparum Dihydroorotate Dehydrogenase Inhibitors with Clinical Candidate Potential

Fluorine Modulates Species Selectivity in the Triazolopyrimidine Class of Plasmodium falciparum Dihydroorotate Dehydrogenase Inhibitors

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9227-9240

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P31

scholarly article

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10.1021/ACSOMEGA.8B01573

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English

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P478

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P50

Jeremy N Burrows

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2018-08-31T00:00:00Z

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30197997

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P932

6120730

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