Structural basis for site-specific ribose methylation by box C/D RNA protein complexes
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Structure ofAeropyrum pernixfibrillarin in complex with natively boundS-adenosyl-L-methionine at 1.7 Å resolutionCrystal structure of RlmM, the 2'O-ribose methyltransferase for C2498 of Escherichia coli 23S rRNAStructurally Conserved Nop56/58 N-terminal Domain Facilitates Archaeal Box C/D Ribonucleoprotein-guided Methyltransferase ActivityStructures of the flax-rust effector AvrM reveal insights into the molecular basis of plant-cell entry and effector-triggered immunityThe structure of the box C/D enzyme reveals regulation of RNA methylationNoncoding RNAs: Possible Players in the Development of FluorosisCo-expression and co-purification of archaeal and eukaryal box C/D RNPsImplication of the box C/D snoRNP assembly factor Rsa1p in U3 snoRNP assembly.RNA structure determination by solid-state NMR spectroscopy.Proteomic and 3D structure analyses highlight the C/D box snoRNP assembly mechanism and its control.Mak5 and Ebp2 act together on early pre-60S particles and their reduced functionality bypasses the requirement for the essential pre-60S factor Nsa1.C/D box sRNA-guided 2'-O-methylation patterns of archaeal rRNA moleculesNUFIP and the HSP90/R2TP chaperone bind the SMN complex and facilitate assembly of U4-specific proteins.Box C/D guide RNAs recognize a maximum of 10 nt of substrates.Molecular architecture of the 90S small subunit pre-ribosomeThe box C/D and H/ACA snoRNPs: key players in the modification, processing and the dynamic folding of ribosomal RNA.Ribonucleoproteins in archaeal pre-rRNA processing and modification.Small nucleolar RNAs and RNA-guided post-transcriptional modification.Transfer RNA methyltransferases with a SpoU-TrmD (SPOUT) fold and their modified nucleosides in tRNA.Assembly and trafficking of box C/D and H/ACA snoRNPsPlasticity of archaeal C/D box sRNA biogenesis.Regulatory role of small nucleolar RNAs in human diseases.Box C/D sRNA stem ends act as stabilizing anchors for box C/D di-sRNPs.Programmable sequence-specific click-labeling of RNA using archaeal box C/D RNP methyltransferases.Nutritional status modulates box C/D snoRNP biogenesis by regulated subcellular relocalization of the R2TP complexUnusual C΄/D΄ motifs enable box C/D snoRNPs to modify multiple sites in the same rRNA target region.Protein-RNA interfaces probed by 1H-detected MAS solid-state NMR spectroscopy.Sequence determinants of the folding properties of box C/D kink-turns in RNA.Nop5 interacts with the archaeal RNA exosome.3.2-Å-resolution structure of the 90S preribosome before A1 pre-rRNA cleavage.Nm-seq maps 2'-O-methylation sites in human mRNA with base precision.Structural Basis for Regulation of Ribosomal RNA 2′-O-Methylation
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Structural basis for site-specific ribose methylation by box C/D RNA protein complexes
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article publié dans la revue scientifique Nature
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scientific article published in Nature
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wetenschappelijk artikel
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наукова стаття, опублікована в Nature в січні 2011
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name
Structural basis for site-specific ribose methylation by box C/D RNA protein complexes
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Structural basis for site-specific ribose methylation by box C/D RNA protein complexes
@nl
type
label
Structural basis for site-specific ribose methylation by box C/D RNA protein complexes
@en
Structural basis for site-specific ribose methylation by box C/D RNA protein complexes
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prefLabel
Structural basis for site-specific ribose methylation by box C/D RNA protein complexes
@en
Structural basis for site-specific ribose methylation by box C/D RNA protein complexes
@nl
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Structural basis for site-specific ribose methylation by box C/D RNA protein complexes
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Jinzhong Lin
Keqiong Ye
Liman Zhang
Shaomei Lai
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10.1038/NATURE09688
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2011-01-01T00:00:00Z
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1053173980