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Pim Kinases Promote Migration and Metastatic Growth of Prostate Cancer XenograftsSynthesis, kinase inhibitory potencies, and in vitro antiproliferative evaluation of new Pim kinase inhibitorsDiscovery of pyrido[3,4-g]quinazoline derivatives as CMGC family protein kinase inhibitors: Design, synthesis, inhibitory potency and X-ray co-crystal structureSyntheses and biological activities of rebeccamycin analogues. Introduction of a halogenoacetyl substituentSynthesis and biological activities of 7-aza rebeccamycin analogues bearing the sugar moiety on the nitrogen of the pyridine ring.Bis-imide granulatimide analogues as potent Checkpoint 1 kinase inhibitors.Syntheses and biological activities (topoisomerase inhibition and antitumor and antimicrobial properties) of rebeccamycin analogues bearing modified sugar moieties and substituted on the imide nitrogen with a methyl group.Synthesis and activities of new indolopyrrolobenzodiazepine derivatives toward acute myeloid leukemia cells.Heteroaromatic Pim Kinase Inhibitors Containing a Pyrazole Moiety.Biological evaluation of glycosyl-isoindigo derivatives against the pathogenic agents of tropical diseases (malaria, Chagas disease, leishmaniasis and human African trypanosomiasis).New N-1,N-10-bridged pyrrolo[2,3-a]carbazole-3-carbaldehydes: synthesis and biological activities.Synthesis of pyrazolo[4,3-a]phenanthridines, a new scaffold for Pim kinase inhibition.Synthesis, protein kinase inhibitory potencies, and in vitro antiproliferative activities of meridianin derivatives.Synthesis and biological activities of pyrazolo[3,4-g]quinoxaline derivatives.Synthesis, Pim kinase inhibitory potencies and in vitro antiproliferative activities of diversely substituted pyrrolo[2,3-a]carbazoles.Synthesis and in vitro antiproliferative activities of quinoline derivatives.Synthesis and biological activities of aminopyrimidyl-indoles structurally related to meridianins.Synthesis, checkpoint kinase 1 inhibitory properties and in vitro antiproliferative activities of new pyrrolocarbazoles.Synthesis and biological activities of new checkpoint kinase 1 inhibitors structurally related to granulatimide.In-vitro antiproliferative activities and kinase inhibitory potencies of glycosyl-isoindigo derivatives.Synthesis and antiproliferative activities of isoindigo and azaisoindigo derivatives.Synthesis and biological activities of isogranulatimide analogues.Synthesis, in vitro antiproliferative activities, and Chk1 inhibitory properties of pyrrolo[3,4-a]carbazole-1,3-diones, pyrrolo[3,4-c]carbazole-1,3-diones, and 2-aminopyridazino[3,4-a]pyrrolo[3,4-c]carbazole-1,3,4,7-tetraone.Synthesis and antiproliferative activities of diversely substituted glycosyl-isoindigo derivatives.Synthesis and cytotoxicities of 7-aza rebeccamycin analogues bearing various substituents on the sugar moiety, on the imide nitrogen and on the carbazole framework.Semi-synthesis, topoisomerase I and kinases inhibitory properties, and antiproliferative activities of new rebeccamycin derivatives.Synthesis and biological activities of new di- and trimeric quinoline derivatives.Identification of pyrrolo[2,3-g]indazoles as new Pim kinase inhibitors.DNA targeting of two new antitumour rebeccamycin derivatives.Rebeccamycin analogues bearing amine substituents or other groups on the sugar moiety.Rebeccamycin derivatives as dual DNA-damaging agents and potent checkpoint kinase 1 inhibitors.Synthesis and preliminary in vitro kinase inhibition evaluation of new diversely substituted pyrido[3,4-g]quinazoline derivatives.Synthesis and biological activity of pyrazole analogues of the staurosporine aglycon K252c.Synthesis, kinase inhibitory potencies and in vitro antiproliferative activity of isoindigo and 7'-azaisoindigo derivatives substituted by Sonogashira cross-coupling.Synthesis and biological activities of 4-substituted pyrrolo[2,3-a]carbazole Pim kinase inhibitors.Kinase inhibitory potencies and in vitro antiproliferative activities of N-10 substituted pyrrolo[2,3-a]carbazole derivatives.Synthesis and molecular modeling study of new trimeric quinoline derivativesA Kinase Inhibitor with Anti-Pim Kinase Activity is a Potent and Selective Cytotoxic Agent Toward Acute Myeloid LeukemiaKinase inhibitions in pyrido[4,3-h] and [3,4-g]quinazolines: Synthesis, SAR and molecular modeling studies
P50
Q27304359-AB18BEE3-2A99-47B5-B0B8-9F3FB7BA1C23Q27657599-7673F777-7396-4DE1-9B46-E798C232731EQ27704741-90BCDAEE-A286-4C22-B009-8C827228FAA0Q28370643-4C59018D-B1D7-45DC-9DE9-D70F444E9F35Q31051767-7F86425B-B04C-4000-BBD8-D3B5412C46BFQ31081401-8FF77614-55DF-4247-A9CA-659DCD5606D6Q34743346-5405B157-5313-4DEE-97EF-AD9D8D869634Q38822742-42B6F946-C328-420B-B024-D67E597542B1Q38838080-CAD484F2-43B8-4648-8152-E9F5FBFCBD2BQ38916617-2546947D-C350-4178-972C-5CA69F08072AQ38948818-B1649125-C01A-4A0A-8604-302AA88F2C4CQ38969249-4E56B8B8-47B1-4AB5-A71C-0E988575ED1CQ39533907-79E9B297-17F1-4463-AA78-1F3072D08C57Q39652219-45708142-AC6F-4AB2-ABF8-9A0887A6371BQ39664916-8E85B543-1748-4748-9152-A17DCF778C83Q39747308-AE8F762D-3139-47B0-AA4A-7AF67FA2D0B0Q39845838-9A93B073-716A-47A6-9C0B-382022536825Q40005679-3419A1D9-A35A-4805-9835-01CD833C8774Q40088926-D0C0158B-BD02-4B1F-9A5B-41ECCC1F9323Q40092647-178CC0A9-C680-4AF8-A529-50D43D8704BEQ40107568-D39EB726-D0B8-4CAE-AA9B-2DECB280FFE7Q40117019-66E2DAE5-B614-4B84-B531-1704663D3B62Q40133097-2F80B58E-A6E7-4FB8-A37F-37F41C847C79Q40343412-CF784FC3-E205-44BA-9C90-B511D76C7634Q40419482-E05A6E8C-9056-4A4B-95DE-31C0AF321C4AQ40618924-C28631CF-93FC-4B6E-A8E4-8820740CB4D7Q42923843-63EA5582-B486-47FC-8309-9A5C66C70AA7Q43583006-67DAE2F4-5839-432C-81EF-476A1F27FC33Q44378610-9E4E0773-3F9E-4B78-B0A4-33589D0EEC4EQ44539056-0DD20660-B009-42B7-9D08-D12E05D5F950Q46392529-35170B04-B1F5-4C03-88CB-D43E63A00745Q51609604-7DA1130B-F193-4912-9CE2-F91D73CB4555Q51723939-BD66BFD4-D79A-488E-B960-C121BC2143A6Q51808958-6C25DF45-DB02-4B89-AB1C-A09ABEBB5E79Q54483392-E93729A9-4A70-4267-B084-E06F0D178959Q54514308-9F9D62D2-6976-4BA0-91EE-397054C88B77Q84635405-35CB93A7-E9A1-4306-A002-5A5BC9D57E5AQ91210508-2449D5F2-E4C6-4B54-8820-A6D601492908Q92984986-667F5008-F615-4B59-A7B4-684C1006B485
P50
description
researcher ORCID ID = 0000-0001-7869-9622
@en
wetenschapper
@nl
name
Fabrice Anizon
@ast
Fabrice Anizon
@en
Fabrice Anizon
@es
Fabrice Anizon
@nl
type
label
Fabrice Anizon
@ast
Fabrice Anizon
@en
Fabrice Anizon
@es
Fabrice Anizon
@nl
prefLabel
Fabrice Anizon
@ast
Fabrice Anizon
@en
Fabrice Anizon
@es
Fabrice Anizon
@nl
P31
P496
0000-0001-7869-9622