about
Live cell imaging of low- and non-repetitive chromosome loci using CRISPR-Cas9Cytoplasmic dynein moves through uncoordinated stepping of the AAA+ ring domainsThe AAA3 domain of cytoplasmic dynein acts as a switch to facilitate microtubule release.Bidirectional helical motility of cytoplasmic dynein around microtubules.Cytoplasmic dynein transports cargos via load-sharing between the heads.Intraflagellar transport drives flagellar surface motility.The mammalian dynein-dynactin complex is a strong opponent to kinesin in a tug-of-war competition.A conformational checkpoint between DNA binding and cleavage by CRISPR-Cas9Tension on the linker gates the ATP-dependent release of dynein from microtubulesDynamics of the IFT machinery at the ciliary tip.Enhanced proofreading governs CRISPR-Cas9 targeting accuracy.Cryo-EM shows how dynactin recruits two dyneins for faster movement.Kinesin and dynein use distinct mechanisms to bypass obstaclesCargo adaptors regulate stepping and force generation of mammalian dynein-dynactinDirectionality of dynein is controlled by the angle and length of its stalkLis1 activates dynein motility by modulating its pairing with dynactin
P50
Q30252964-108FB4CD-2F59-4C1C-B2EA-3CE9A0C3EA76Q30578826-BE18FF17-12E2-4E49-9047-7B0051771E54Q30613343-C85747CE-0197-4D98-89AB-58C95770C2B8Q34063304-63D2E485-DE62-4E02-8893-2251C793DA85Q35541625-0D42E802-DFC1-47E5-9AB5-C741641B762DQ36921036-FDA1816E-FB7F-4477-986F-A34C9BA4A35FQ40989404-28DF610D-37F7-452D-BCBB-E3A2F6CE9980Q41294785-3F27F237-2E87-4D4D-BF5E-3EBAF9B5D18CQ42230329-D18CB0CB-E538-4F82-B2CD-314A534E138EQ42515452-6B1BF96B-E06A-4C58-B957-95CA944DEE69Q46347859-B95D7CA7-10B8-43E0-9A9A-12947C64D102Q50115001-272DD517-F72A-4DCC-8F6B-90906071DB06Q83228048-DF52B522-48E4-4196-A922-3C2B4F4CC906Q90003704-160C5C18-5FD7-41AE-9A55-769528475F68Q91387378-9D4B8AEE-1148-406D-B478-9136A41CE344Q93270860-056928F4-2D32-42B6-B81B-6E355519B21E
P50
description
researcher ORCID ID = 0000-0003-4792-174X
@en
name
Ahmet Yildiz
@ast
Ahmet Yildiz
@en
Ahmet Yildiz
@es
Ahmet Yildiz
@nl
type
label
Ahmet Yildiz
@ast
Ahmet Yildiz
@en
Ahmet Yildiz
@es
Ahmet Yildiz
@nl
prefLabel
Ahmet Yildiz
@ast
Ahmet Yildiz
@en
Ahmet Yildiz
@es
Ahmet Yildiz
@nl
P31
P496
0000-0003-4792-174X