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Neutrophil mobilization by surface-glycan altered Th17-skewing bacteria mitigates periodontal pathogen persistence and associated alveolar bone lossTLR2 signaling and Th2 responses drive Tannerella forsythia-induced periodontal bone loss.Fusobacterium nucleatum and Tannerella forsythia induce synergistic alveolar bone loss in a mouse periodontitis model.Macrophage inducible C-type lectin (Mincle) recognizes glycosylated surface (S)-layer of the periodontal pathogen Tannerella forsythia.Protein-linked glycans in periodontal bacteria: prevalence and role at the immune interface.Bacteria take control of tolls and T cells to destruct jaw bone.Genetic characteristics and pathogenic mechanisms of periodontal pathogens.Tannerella forsythia-produced methylglyoxal causes accumulation of advanced glycation endproducts to trigger cytokine secretion in human monocytes.
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description
researcher ORCID ID = 0000-0002-3577-7675
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wetenschapper
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name
Rajendra P Settem
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Rajendra P Settem
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Rajendra P Settem
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type
label
Rajendra P Settem
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Rajendra P Settem
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Rajendra P Settem
@nl
prefLabel
Rajendra P Settem
@ast
Rajendra P Settem
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Rajendra P Settem
@nl
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P31
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0000-0002-3577-7675