about
Maturation of induced pluripotent stem cell derived hepatocytes by 3D-cultureHex homeobox gene-dependent tissue positioning is required for organogenesis of the ventral pancreasInteraction between Hhex and SOX13 modulates Wnt/TCF activitySilencing of hepatic fate-conversion factors induce tumorigenesis in reprogrammed hepatic progenitor-like cells.Early ERK1/2 activation promotes DRP1-dependent mitochondrial fission necessary for cell reprogramming.Growth-promoting and tumourigenic activity of c-Myc is suppressed by Hhex.A combination of transcriptomics and metabolomics uncovers enhanced bile acid biosynthesis in HepG2 cells expressing CCAAT/enhancer-binding protein β (C/EBPβ), hepatocyte nuclear factor 4α (HNF4α), and constitutive androstane receptor (CAR).Transcriptomic responses generated by hepatocarcinogens in a battery of liver-based in vitro models.Gata4 blocks somatic cell reprogramming by directly repressing Nanog.Role of hepatocyte nuclear factor 3 gamma in the expression of human CYP2C genes.Biotransformation in vitro of the 22R and 22S epimers of budesonide by human liver, bronchus, colonic mucosa and skin.Transfection of Primary Hepatocytes with Liver-Enriched Transcription Factors Using Adenoviral Vectors.Increased toxicity of cocaine on human hepatocytes induced by ethanol: role of GSH.Hepatic cytochrome P450 down-regulation during aseptic inflammation in the mouse is interleukin 6 dependentRe-expression of C/EBPα induces CYP2B6, CYP2C9 and CYP2D6 genes in HepG2 cellsMolecular mechanism of diclofenac hepatotoxicity: Association of cell injury with oxidative metabolism and decrease in ATP levelsPurification and characterization of a new α-amylase of intermediate thermal stability from the yeast Lipomyces kononenkoaeLong-term expression of differentiated functions in hepatocytes cultured in three-dimensional collagen matrixPaths to the pancreasDirect conversion of human fibroblast to hepatocytes using a single inducible polycistronic vectorGlutamine/glutamate metabolism rewiring in reprogrammed human hepatocyte-like cells
P50
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P50
description
onderzoeker
@nl
researcher ORCID ID = 0000-0002-7285-0536
@en
name
Roque Bort
@ast
Roque Bort
@en
Roque Bort
@es
Roque Bort
@nl
type
label
Roque Bort
@ast
Roque Bort
@en
Roque Bort
@es
Roque Bort
@nl
altLabel
Bort R
@en
prefLabel
Roque Bort
@ast
Roque Bort
@en
Roque Bort
@es
Roque Bort
@nl
P108
P106
P21
P31
P496
0000-0002-7285-0536