about
Pur-alpha regulates cytoplasmic stress granule dynamics and ameliorates FUS toxicity.Antisense proline-arginine RAN dipeptides linked to C9ORF72-ALS/FTD form toxic nuclear aggregates that initiate in vitro and in vivo neuronal death.Depalmitoylation preferentially downregulates AMPA induced Ca2+ signaling and neurotoxicity in motor neurons.Astrocytes expressing ALS-linked mutant FUS induce motor neuron death through release of tumor necrosis factor-alpha.AAV2-BDNF promotes respiratory axon plasticity and recovery of diaphragm function following spinal cord injuryMuscleblind acts as a modifier of FUS toxicity by modulating stress granule dynamics and SMN localizationSynaptic dysfunction induced by glycine-alanine dipeptides in C9orf72-ALS/FTD is rescued by SV2 replenishment
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description
researcher ORCID ID = 0000-0003-2552-8912
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wetenschapper
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name
Karthik Krishnamurthy
@ast
Karthik Krishnamurthy
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Karthik Krishnamurthy
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Karthik Krishnamurthy
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type
label
Karthik Krishnamurthy
@ast
Karthik Krishnamurthy
@en
Karthik Krishnamurthy
@es
Karthik Krishnamurthy
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prefLabel
Karthik Krishnamurthy
@ast
Karthik Krishnamurthy
@en
Karthik Krishnamurthy
@es
Karthik Krishnamurthy
@nl
P1153
54403049700
P31
P496
0000-0003-2552-8912