about
A high-fat diet and NAD(+) activate Sirt1 to rescue premature aging in cockayne syndromePoly(ADP-ribose)-mediated interplay of XPA and PARP1 leads to reciprocal regulation of protein function.RecQ helicases and PARP1 team up in maintaining genome integrity.An automated Fpg-based FADU method for the detection of oxidative DNA lesions and screening of antioxidantsChemistry meets biology in colitis-associated carcinogenesisDifferential and Concordant Roles for Poly(ADP-Ribose) Polymerase 1 and Poly(ADP-Ribose) in Regulating WRN and RECQL5 Activities.Infection-induced colitis in mice causes dynamic and tissue-specific changes in stress response and DNA damage leading to colon cancer.Site-specific noncovalent interaction of the biopolymer poly(ADP-ribose) with the Werner syndrome protein regulates protein functions.Chemical and cytokine features of innate immunity characterize serum and tissue profiles in inflammatory bowel diseaseIncreased levels of inosine in a mouse model of inflammationQuantification of cellular poly(ADP-ribosyl)ation by stable isotope dilution mass spectrometry reveals tissue- and drug-dependent stress response dynamicsHow to kill tumor cells with inhibitors of poly(ADP-ribosyl)ation.Immunochemical analysis of poly(ADP-ribosyl)ation in HaCaT keratinocytes induced by the mono-alkylating agent 2-chloroethyl ethyl sulfide (CEES): Impact of experimental conditions.Sulfur and nitrogen mustards induce characteristic poly(ADP-ribosyl)ation responses in HaCaT keratinocytes with distinctive cellular consequences.Mechanisms of Hg species induced toxicity in cultured human astrocytes: genotoxicity and DNA-damage response.Toxicological properties of the thiolated inorganic arsenic and arsenosugar metabolite thio-dimethylarsinic acid in human bladder cells.A caveat in mouse genetic engineering: ectopic gene targeting in ES cells by bidirectional extension of the homology arms of a gene replacement vector carrying human PARP-1.Inflammatory and age-related pathologies in mice with ectopic expression of human PARP-1.Mass spectrometric analysis of sulfur mustard-induced biomolecular adducts: Are DNA adducts suitable biomarkers of exposure?The C-terminal domain of p53 orchestrates the interplay between non-covalent and covalent poly(ADP-ribosyl)ation of p53 by PARP1.PARP1 protects from benzo[a]pyrene diol epoxide-induced replication stress and mutagenicity.Chemical warfare in the First World War: reflections 100 years later.Quantitation of Poly(ADP-Ribose) by Isotope Dilution Mass Spectrometry.PARP-1 protects against colorectal tumor induction, but promotes inflammation-driven colorectal tumor progression.Day and night variations in the repair of ionizing-radiation-induced DNA damage in mouse splenocytes.A mass spectrometric platform for the quantitation of sulfur mustard-induced nucleic acid adducts as mechanistically relevant biomarkers of exposureInteractions of p53 with poly(ADP-ribose) and DNA induce distinct changes in protein structure as revealed by ATR-FTIR spectroscopyA novel exposure system generating nebulized aerosol of sulfur mustard in comparison to the standard submerse exposureNAD+ augmentation restores mitophagy and limits accelerated aging in Werner syndromePARP1 regulates DNA damage-induced nucleolar-nucleoplasmic shuttling of WRN and XRCC1 in a toxicant and protein-specific mannerRestriction of AID activity and somatic hypermutation by PARP-1Comparison of Aristolochic acid I derived DNA adduct levels in human renal toxicity modelsReal-time monitoring of PARP1-dependent PARylation by ATR-FTIR spectroscopy
P50
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P50
description
researcher ORCID ID = 0000-0001-9742-2338
@en
name
Aswin Mangerich
@ast
Aswin Mangerich
@en
Aswin Mangerich
@es
Aswin Mangerich
@nl
type
label
Aswin Mangerich
@ast
Aswin Mangerich
@en
Aswin Mangerich
@es
Aswin Mangerich
@nl
prefLabel
Aswin Mangerich
@ast
Aswin Mangerich
@en
Aswin Mangerich
@es
Aswin Mangerich
@nl
P31
P496
0000-0001-9742-2338