about
Wnt4 participates in the formation of vertebrate neuromuscular junctionUp-regulation of WNT-4 signaling and dosage-sensitive sex reversal in humans.SOX9 elevation in the prostate promotes proliferation and cooperates with PTEN loss to drive tumor formationBrca2 and Trp53 deficiency cooperate in the progression of mouse prostate tumourigenesisDNA-Repair Defects and Olaparib in Metastatic Prostate CancerAdrenal development is initiated by Cited2 and Wt1 through modulation of Sf-1 dosageDax1 antagonizes Sry action in mammalian sex determinationFollistatin operates downstream of Wnt4 in mammalian ovary organogenesisSox9 is required for prostate developmentThe transcription co-factor CITED2 functions during sex determination and early gonad developmentSex specific retinoic acid signaling is required for the initiation of urogenital sinus bud development.β-catenin is required for prostate development and cooperates with Pten loss to drive invasive carcinoma.Pten Regulates Epithelial Cytodifferentiation during Prostate Development.Genome-wide barcoded transposon screen for cancer drug sensitivity in haploid mouse embryonic stem cells.Mechanisms of Disease: normal and abnormal gonadal development and sex determination in mammals.The role of Sox9 in prostate development.Gene dosage effects and transcriptional regulation of early mammalian adrenal cortex development.High-Level Clonal FGFR Amplification and Response to FGFR Inhibition in a Translational Clinical TrialWhole-exome DNA sequence analysis of Brca2- and Trp53-deficient mouse mammary gland tumours.CHD1 loss sensitizes prostate cancer to DNA damaging therapy by promoting error-prone double-strand break repair.Prostate Organogenesis.SOX9 is a driver of aggressive prostate cancer by promoting invasion, cell fate and cytoskeleton alterations and epithelial to mesenchymal transition.Ductal sex determination.Sex determination: time for meiosis? The gonad decides.Targeting Bromodomain and Extra-Terminal (BET) Family Proteins in Castration-Resistant Prostate Cancer (CRPC).Genome-wide and high-density CRISPR-Cas9 screens identify point mutations in PARP1 causing PARP inhibitor resistance.Wnt4/β-Catenin Signaling Induces VSMC Proliferation and Is Associated With Intimal ThickeningIdentification of a novel population of adrenal-like cells in the mammalian testis
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P50
description
researcher ORCID ID = 0000-0001-8666-1608
@en
name
Amanda Swain
@ast
Amanda Swain
@en
Amanda Swain
@es
Amanda Swain
@nl
type
label
Amanda Swain
@ast
Amanda Swain
@en
Amanda Swain
@es
Amanda Swain
@nl
prefLabel
Amanda Swain
@ast
Amanda Swain
@en
Amanda Swain
@es
Amanda Swain
@nl
P21
P31
P496
0000-0001-8666-1608