about
Neuregulin and BDNF induce a switch to NMDA receptor-dependent myelination by oligodendrocytesCNS Remyelination and the Innate Immune SystemAgeing stem and progenitor cells: implications for rejuvenation of the central nervous systemMyelin impairs CNS remyelination by inhibiting oligodendrocyte precursor cell differentiationMyelin-mediated inhibition of oligodendrocyte precursor differentiation can be overcome by pharmacological modulation of Fyn-RhoA and protein kinase C signallingDysregulation of the Wnt pathway inhibits timely myelination and remyelination in the mammalian CNSPromotion of central nervous system remyelination by induced differentiation of oligodendrocyte precursor cellsAge-dependent epigenetic control of differentiation inhibitors is critical for remyelination efficiencyIncreased mitochondrial content in remyelinated axons: implications for multiple sclerosis.Autologous olfactory mucosal cell transplants in clinical spinal cord injury: a randomized double-blinded trial in a canine translational modelCNS-resident glial progenitor/stem cells produce Schwann cells as well as oligodendrocytes during repair of CNS demyelination.MRI measurements of reporter-mediated increases in transmembrane water exchange enable detection of a gene reporter.Mechanical difference between white and gray matter in the rat cerebellum measured by scanning force microscopy.Astrocyte response to motor neuron injury promotes structural synaptic plasticity via STAT3-regulated TSP-1 expression.Oligodendrocyte PTEN is required for myelin and axonal integrity, not remyelinationWhat roles do growth factors play in CNS remyelination?The Complement Receptor C5aR Controls Acute Inflammation and Astrogliosis following Spinal Cord Injury.Remyelination by transplanted olfactory ensheathing cells.Glia Disease and Repair-RemyelinationFibroblast growth factor signaling in oligodendrocyte-lineage cells facilitates recovery of chronically demyelinated lesions but is redundant in acute lesions.Astrocyte Activation via Stat3 Signaling Determines the Balance of Oligodendrocyte versus Schwann Cell RemyelinationNeuronal activity regulates remyelination via glutamate signalling to oligodendrocyte progenitorsMechanisms of CNS remyelination--the key to therapeutic advances.Stem cells, progenitors and myelin repair.Retinoid X receptor activation reverses age-related deficiencies in myelin debris phagocytosis and remyelinationVitamin D receptor-retinoid X receptor heterodimer signaling regulates oligodendrocyte progenitor cell differentiationPioglitazone regulates myelin phagocytosis and multiple sclerosis monocytes.Clinical canine spinal cord injury provides an opportunity to examine the issues in translating laboratory techniques into practical therapy.Injury and differentiation following inhibition of mitochondrial respiratory chain complex IV in rat oligodendrocytesPre-Existing Mature Oligodendrocytes Do Not Contribute to Remyelination following Toxin-Induced Spinal Cord Demyelination.Micropillar arrays as a high-throughput screening platform for therapeutics in multiple sclerosis.Promoting remyelination in multiple sclerosis by endogenous adult neural stem/precursor cells: defining cellular targets.Neuregulin-1/ErbB signaling serves distinct functions in myelination of the peripheral and central nervous system.Debris clearance by microglia: an essential link between degeneration and regeneration.The biology of CNS remyelination: the key to therapeutic advances.Axonal plasticity underpins the functional recovery following surgical decompression in a rat model of cervical spondylotic myelopathyThe late response of rat subependymal zone stem and progenitor cells to stroke is restricted to directly affected areas of their niche.High yields of oligodendrocyte lineage cells from human embryonic stem cells at physiological oxygen tensions for evaluation of translational biology.Electric Signals Regulate the Directional Migration of Oligodendrocyte Progenitor Cells (OPCs) via β1 Integrin.Neurodegeneration progresses despite complete elimination of clinical relapses in a mouse model of multiple sclerosis
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description
researcher ORCID ID = 0000-0001-6522-2104
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wetenschapper
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Robin J.M. Franklin
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Robin J.M. Franklin
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Robin J.M. Franklin
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Robin J.M. Franklin
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type
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Robin J.M. Franklin
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Robin J.M. Franklin
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Robin J.M. Franklin
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Robin J.M. Franklin
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prefLabel
Robin J.M. Franklin
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Robin J.M. Franklin
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Robin J.M. Franklin
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Robin J.M. Franklin
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P108
P31
P496
0000-0001-6522-2104