about
Broad-minded links cell cycle-related kinase to cilia assembly and hedgehog signal transductionIntestinal cell kinase, a protein associated with endocrine-cerebro-osteodysplasia syndrome, is a key regulator of cilia length and Hedgehog signalingCapsaicin prevents degeneration of dopamine neurons by inhibiting glial activation and oxidative stress in the MPTP model of Parkinson's disease.A hierarchical phosphorylation cascade that regulates the timing of PERIOD nuclear entry reveals novel roles for proline-directed kinases and GSK-3beta/SGG in circadian clocks.Two distinct modes of PERIOD recruitment onto dCLOCK reveal a novel role for TIMELESS in circadian transcription.Effects of substrate conductivity on cell morphogenesis and proliferation using tailored, atomic layer deposition-grown ZnO thin filmsLeptin Elongates Hypothalamic Neuronal Cilia via Transcriptional Regulation and Actin DestabilizationPrimary cilia in energy balance signaling and metabolic disorder.Natural variation in the splice site strength of a clock gene and species-specific thermal adaptation.Leptin-promoted cilia assembly is critical for normal energy balanceSingle-stranded DNA aptamer that specifically binds to the influenza virus NS1 protein suppresses interferon antagonism.Cell Cycle-Related Kinase (CCRK) regulates ciliogenesis and Hedgehog signaling in mice.Sulforaphene Interferes with Human Breast Cancer Cell Migration and Invasion through Inhibition of Hedgehog Signaling.Vaccinia-related kinase 3 (VRK3) sets the circadian period and amplitude by affecting the subcellular localization of clock proteins in mammalian cells.Drosophila peptidyl-prolyl isomerase Pin1 modulates circadian rhythms via regulating levels of PERIOD.An inactivating mutation in intestinal cell kinase, ICK, impairs hedgehog signalling and causes short rib-polydactyly syndrome.Role for Slimb in the degradation of Drosophila Period protein phosphorylated by Doubletime.Design, synthesis, and biological evaluation of structurally modified isoindolinone and quinazolinone derivatives as hedgehog pathway inhibitors.Mangosteen Extract Prevents Dextran Sulfate Sodium-Induced Colitis in Mice by Suppressing NF-κB Activation and Inflammation.Injury-stimulated Sonic hedgehog expression in microglia contributes to neuroinflammatory response in the MPTP model of Parkinson's disease.PEGylated hyaluronic acid-coated liposome for enhanced in vivo efficacy of sorafenib via active tumor cell targeting and prolonged systemic exposure.Pax3 function is required specifically for inner ear structures with melanogenic fates.α-Mangostin ameliorates dextran sulfate sodium-induced colitis through inhibition of NF-κB and MAPK pathways.Localization of primary cilia in mouse retina.Paclitaxel-Nanodiamond Nanocomplexes Enhance Aqueous Dispersibility and Drug Retention in Cells.Ciliary smoothened-mediated noncanonical hedgehog signaling promotes tubulin acetylation.Fluoxetine prevents MPTP-induced loss of dopaminergic neurons by inhibiting microglial activation.Fibroblast growth factor receptor influences primary cilium length through an interaction with intestinal cell kinaseNuclear factor kappa B-mediated kainate neurotoxicity in the rat and hamster hippocampusSynergetic activation of p38 mitogen-activated protein kinase and caspase-3-like proteases for execution of calyculin A-induced apoptosis but not N-methyl-d-aspartate-induced necrosis in mouse cortical neuronsNT-4/5 exacerbates free radical-induced neuronal necrosis in vitro and in vivo
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description
researcher ORCID ID = 0000-0003-1753-1900
@en
wetenschapper
@nl
name
Hyuk Wan Ko
@ast
Hyuk Wan Ko
@en
Hyuk Wan Ko
@es
Hyuk Wan Ko
@nl
type
label
Hyuk Wan Ko
@ast
Hyuk Wan Ko
@en
Hyuk Wan Ko
@es
Hyuk Wan Ko
@nl
altLabel
HYUK WAN KO
@en
prefLabel
Hyuk Wan Ko
@ast
Hyuk Wan Ko
@en
Hyuk Wan Ko
@es
Hyuk Wan Ko
@nl
P106
P1153
7201926263
P31
P496
0000-0003-1753-1900