about
Engineered chimeric enzymes as tools for drug discovery: generating reliable bacterial screens for the detection, discovery, and assessment of estrogen receptor modulators.Novel dehydroepiandrosterone derivatives with antiapoptotic, neuroprotective activity.Estrogenic activity of isoflavonoids from the stem bark of the tropical tree Amphimas pterocarpoides, a source of traditional medicines.Biological and computational evaluation of resveratrol inhibitors against Alzheimer's disease.Pharmacoproteomic study of the natural product Ebenfuran III in DU-145 prostate cancer cells: the quantitative and temporal interrogation of chemically induced cell death at the protein level.Peltogynoids and 2-phenoxychromones from Peltophorum pterocarpum and evaluation of their estrogenic activity.Ester and carbamate ester derivatives of Biochanin A: synthesis and in vitro evaluation of estrogenic and antiproliferative activities.Insights into ectopic estrogen receptor expression, nucleocytoplasmic distribution and interaction with chromatin obtained with new antibodies to estrogen receptors α and β.Phytochemical study and biological evaluation of chemical constituents of Platanus orientalis and Platanus × acerifolia buds.Differential estrogen receptor subtype modulators: assessment of estrogen receptor subtype-binding selectivity and transcription-regulating properties of new cycloalkyl pyrazoles.5alpha,8alpha-Epidioxysterols from the gorgonian Eunicella cavolini and the ascidian Trididemnum inarmatum: isolation and evaluation of their antiproliferative activity.A novel quantitative flow cytometric method for measuring glucocorticoid receptor (GR) in cell lines: correlation with the biochemical determination of GR.Estrogenic activity of isoflavonoids from Onobrychis ebenoides.Chroman/catechol hybrids: synthesis and evaluation of their activity against oxidative stress induced cellular damage.Microarray analysis of the differential transformation mediated by Kirsten and Harvey Ras oncogenes in a human colorectal adenocarcinoma cell line.A new class of phytoestrogens; evaluation of the estrogenic activity of deoxybenzoins.Regulation of tyrosine aminotransferase gene expression by glucocorticoids in quiescent and regenerating liver.Perinatal exposure to low-dose bisphenol A affects the neuroendocrine stress response in rats.Isoflavonoids from Erythrina poeppigiana: evaluation of their binding affinity for the estrogen receptor.Estrogen receptor beta 2 is associated with poor prognosis in estrogen receptor alpha-negative breast carcinoma.Quantitative fluorescence cytometric measurement of estrogen and progesterone receptors: correlation with the hormone binding assay.Ebenfurans IV-VIII from Onobrychis ebenoides: evidence that C-prenylation is the key determinant of the cytotoxicity of 3-formyl-2-arylbenzofurans.Pronounced enhancement of glucocorticoid-induced gene expression following severe heat shock of heat-conditioned cells hints to intricate cell survival tactics.High affinity 17alpha-substituted estradiol derivatives: synthesis and evaluation of estrogen receptor agonist activity.Spatial performance and corticosteroid receptor status in the 21-day restraint stress paradigm.Maintenance of glucocorticoid receptor function following severe heat-shock of heat-conditioned cells.Isoxazole substituted chromans against oxidative stress-induced neuronal damage.Glucocorticoid receptor gene expression in the embryonic rat brain.Estrogen receptors β1 and β2 are associated with distinct responses of estrogen receptor α-positive breast carcinoma to adjuvant endocrine therapy.Discovery of New Non-steroidal Selective Glucocorticoid Receptor AgonistsCytotoxic effects of 2-arylbenzofuran phytoestrogens on human cancer cells: Modulation by adrenal and gonadal steroidsThe estrogen receptor and polyphenols: molecular simulation studies of their interactions, a reviewBiological evaluation of isoflavonoids from Genista halacsyi using estrogen-target cells: Activities of glucosides compared to aglyconesGlucocorticoid receptors in developing rat brain and liverInteraction of skeletal myosin light chains with calcium ionsSubunit composition of the untransformed glucocorticoid receptor in the cytosol and in the cellPhosphorylation and the binding of calcium and magnesium to skeletal myosinActivation and changes in the sedimentation properties of rat liver glucocorticoid receptorTemporary loss of glucocorticoid receptor-mediated regulation of gene expression in heat-shocked cellsThe efficiency of nuclear processing of the tyrosine aminotransferase mRNA transcript increases after partial hepatectomy
P50
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P50
description
researcher ORCID ID = 0000-0002-4243-7628
@en
name
Michael N Alexis
@ast
Michael N Alexis
@en
Michael N Alexis
@es
Michael N Alexis
@nl
type
label
Michael N Alexis
@ast
Michael N Alexis
@en
Michael N Alexis
@es
Michael N Alexis
@nl
prefLabel
Michael N Alexis
@ast
Michael N Alexis
@en
Michael N Alexis
@es
Michael N Alexis
@nl
P1153
7005403042
P31
P496
0000-0002-4243-7628