about
The accessible chromatin landscape of the human genomeDirect GR Binding Sites Potentiate Clusters of TF Binding across the Human Genome.Interactions of chromatin context, binding site sequence content, and sequence evolution in stress-induced p53 occupancy and transactivation.A region of the nucleosome required for multiple types of transcriptional silencing in Saccharomyces cerevisiae.Regulation of chromatin accessibility and Zic binding at enhancers in the developing cerebellum.Genome-wide specificity of DNA binding, gene regulation, and chromatin remodeling by TALE- and CRISPR/Cas9-based transcriptional activatorsGenomic analysis reveals distinct mechanisms and functional classes of SOX10-regulated genes in melanocytes.Genetic variants and cellular stressors associated with exfoliation syndrome modulate promoter activity of a lncRNA within the LOXL1 locus.CRISPR-Cas9 epigenome editing enables high-throughput screening for functional regulatory elements in the human genome.Highly specific epigenome editing by CRISPR-Cas9 repressors for silencing of distal regulatory elementsEvolution of new function through a single amino acid change in the yeast repressor Sum1pPatterns of regulatory activity across diverse human cell types predict tissue identity, transcription factor binding, and long-range interactions.Differential contribution of cis-regulatory elements to higher order chromatin structure and expression of the CFTR locusRole for the pleckstrin homology domain-containing protein CKIP-1 in phosphatidylinositol 3-kinase-regulated muscle differentiation.Inhibition of Cdc25 phosphatases by indolyldihydroxyquinones.Autophosphorylation of Ser66 on Xenopus Myt1 is a prerequisite for meiotic inactivation of Myt1.Variation in DNA-Damage Responses to an Inhalational Carcinogen (1,3-Butadiene) in Relation to Strain-Specific Differences in Chromatin Accessibility and Gene Transcription Profiles in C57BL/6J and CAST/EiJ Mice.Tissue- and strain-specific effects of a genotoxic carcinogen 1,3-butadiene on chromatin and transcription.Comparative Serum Challenges Show Divergent Patterns of Gene Expression and Open Chromatin in Human and Chimpanzee.Experimental validation of the docking orientation of Cdc25 with its Cdk2-CycA protein substrate.Glucocorticoid receptor recruits to enhancers and drives activation by motif-directed bindingHuman cardiac -regulatory elements, their cognate transcription factors, and regulatory DNA sequence variantsTranscriptome and epigenome landscape of human cortical development modeled in organoids
P50
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P50
description
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Alexias Safi
@ast
Alexias Safi
@en
Alexias Safi
@es
Alexias Safi
@nl
type
label
Alexias Safi
@ast
Alexias Safi
@en
Alexias Safi
@es
Alexias Safi
@nl
prefLabel
Alexias Safi
@ast
Alexias Safi
@en
Alexias Safi
@es
Alexias Safi
@nl
P106
P31
P496
0000-0001-6381-4923