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Mx1-based resistance to thogoto virus in A2G mice is bypassed in tick-mediated virus deliveryIn vitro polymerase activity of Thogoto virus: evidence for a unique cap-snatching mechanism in a tick-borne orthomyxovirusStriking conformational similarities between the transcription promoters of Thogoto and influenza A viruses: evidence for intrastrand base pairing in the 5' promoter armMorphogenesis of Plasmodium zoites is uncoupled from tensile strength.IMC1b is a putative membrane skeleton protein involved in cell shape, mechanical strength, motility, and infectivity of malaria ookinetesTranslational repression controls temporal expression of the Plasmodium berghei LCCL protein complexIndian hedgehog (Ihh) both promotes and restricts thymocyte differentiationThe transcription factor Gli3 regulates differentiation of fetal CD4- CD8- double-negative thymocytes.A malaria membrane skeletal protein is essential for normal morphogenesis, motility, and infectivity of sporozoitesThe Plasmodium alveolin IMC1a is stabilised by its terminal cysteine motifs and facilitates sporozoite morphogenesis and infectivity in a dose-dependent mannerPlasmodium alveolins possess distinct but structurally and functionally related multi-repeat domainsBiogenesis of the crystalloid organelle in Plasmodium involves microtubule-dependent vesicle transport and assemblyPlasmodium berghei crystalloids contain multiple LCCL proteinsPbSR is synthesized in macrogametocytes and involved in formation of the malaria crystalloidsLCCL protein complex formation in Plasmodium is critically dependent on LAP1Vital functions of the malarial ookinete protein, CTRP, reside in the A domains.CTRP is essential for mosquito infection by malaria ookinetesCharacterisation and expression of pbs25, a sexual and sporogonic stage specific protein of Plasmodium berghei.Palmitoylation of Plasmodium alveolins promotes cytoskeletal function.Distinct temporal recruitment of Plasmodium alveolins to the subpellicular networkMalaria IMC1 membrane skeleton proteins operate autonomously and participate in motility independently of cell shape.Malaria crystalloids: specialized structures for parasite transmission?The role of metacaspase 1 in Plasmodium berghei development and apoptosis.Conformational co-dependence between Plasmodium berghei LCCL proteins promotes complex formation and stability.LCCL proteins of apicomplexan parasites.Maternally supplied S-acyl-transferase is required for crystalloid organelle formation and transmission of the malaria parasite.A potent series targeting the malarial cGMP-dependent protein kinase clears infection and blocks transmission.Beta-selection: abundance of TCRbeta-/gammadelta- CD44- CD25- (DN4) cells in the foetal thymus.The complete nucleotide sequence of barley mild mosaic virus RNA1 and its relationship with other members of the Potyviridae.A malaria scavenger receptor-like protein essential for parasite development.Functional characterization of an LCCL-lectin domain containing protein family in Plasmodium berghei.35S promoter-driven cDNAs of barley mild mosaic virus RNA1 and RNA2 are infectious on barley plants.Primary structure and sequence analysis of RNA2 of a mechanically transmitted barley mild mosaic virus isolate: an evolutionary relationship between bymo- and furoviruses.The role of LCCL proteins in malaria transmission.Detection of malaria sporozoites expelled during mosquito sugar feeding.The Thogoto orthomyxovirus cRNA promoter functions as a panhandle but does not stimulate cap snatching in vitroThe Plasmodium LAP complex affects crystalloid biogenesis and oocyst cell divisionSpecies-specific alterations in Anopheles mosquito olfactory responses caused by Plasmodium infectionDysregulated gene expression in oocysts of Plasmodium berghei LAP mutantsDistinct Functional Contributions by the Conserved Domains of the Malaria Parasite Alveolin IMC1h.
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P50
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հետազոտող
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Johannes T Dessens
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Johannes T Dessens
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Johannes T Dessens
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Johannes T Dessens
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Johannes T Dessens
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Johannes T Dessens
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P106
P31
P4012
P496
0000-0002-2070-6073