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DNA glycosylases involved in base excision repair may be associated with cancer risk in BRCA1 and BRCA2 mutation carriersStable interaction between the products of the BRCA1 and BRCA2 tumor suppressor genes in mitotic and meiotic cellsTex14, a Plk1-regulated protein, is required for kinetochore-microtubule attachment and regulation of the spindle assembly checkpointCharacterization of EZH1, a human homolog of Drosophila Enhancer of zeste near BRCA1Genome-wide association studies identify four ER negative-specific breast cancer risk lociGenome-wide association study identifies novel breast cancer susceptibility lociAssociation of mitotic regulation pathway polymorphisms with pancreatic cancer risk and outcomeCommon breast cancer-predisposition alleles are associated with breast cancer risk in BRCA1 and BRCA2 mutation carriersA guide for functional analysis of BRCA1 variants of uncertain significanceGenome-wide association study in BRCA1 mutation carriers identifies novel loci associated with breast and ovarian cancer riskDual recognition of phosphoserine and phosphotyrosine in histone variant H2A.X by DNA damage response protein MCPH1Molecular Basis for the Association of Microcephalin (MCPH1) Protein with the Cell Division Cycle Protein 27 (Cdc27) Subunit of the Anaphase-promoting Complex17q23 amplifications in breast cancer involve the PAT1, RAD51C, PS6K, and SIGma1B genesAssignment of the human gene for the alpha 1 subunit of the skeletal muscle DHP-sensitive Ca2+ channel (CACNL1A3) to chromosome 1q31-q32A candidate tumor suppressor HtrA1 is downregulated in ovarian cancerLarge-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repairMutational analysis of thirty-two double-strand DNA break repair genes in breast and pancreatic cancersLocalization of the human homolog of the yeast cell division control 27 gene (CDC27) proximal to ITGB3 on human chromosome 17q21.3Generation of an integrated transcription map of the BRCA2 region on chromosome 13q12-q13Construction of a transcription map surrounding the BRCA1 locus of human chromosome 17A two-gene expression ratio of homeobox 13 and interleukin-17B receptor for prediction of recurrence and survival in women receiving adjuvant tamoxifenCandidate locus analysis of the TERT-CLPTM1L cancer risk region on chromosome 5p15 identifies multiple independent variants associated with endometrial cancer riskGenome-Wide Meta-Analyses of Breast, Ovarian, and Prostate Cancer Association Studies Identify Multiple New Susceptibility Loci Shared by at Least Two Cancer TypesPALB2, CHEK2 and ATM rare variants and cancer risk: data from COGSComparison of mRNA splicing assay protocols across multiple laboratories: recommendations for best practice in standardized clinical testingIdentification of inherited genetic variations influencing prognosis in early-onset breast cancerLarge-scale genotyping identifies 41 new loci associated with breast cancer risk.Genetic modifiers of menopausal hormone replacement therapy and breast cancer risk: a genome-wide interaction study.Genome-wide association study identifies 25 known breast cancer susceptibility loci as risk factors for triple-negative breast cancer.Genetically Predicted Body Mass Index and Breast Cancer Risk: Mendelian Randomization Analyses of Data from 145,000 Women of European DescentIdentification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer.Classifying Variants of Undetermined Significance in BRCA2 with protein likelihood ratios.No clinical utility of KRAS variant rs61764370 for ovarian or breast cancer.Classification of missense substitutions in the BRCA genes: a database dedicated to Ex-UVs.Racial disparity in breast cancer and functional germ line mutation in galectin-3 (rs4644): a pilot study.BRCA2 localization to the midbody by filamin A regulates cep55 signaling and completion of cytokinesis.Crowdsourcing the General Public for Large Scale Molecular Pathology Studies in Cancer.Collaborative science in the next-generation sequencing era: a viewpoint on how to combine exome sequencing data across sites to identify novel disease susceptibility genes.Male breast cancer in BRCA1 and BRCA2 mutation carriers: pathology data from the Consortium of Investigators of Modifiers of BRCA1/2.Comparison of 6q25 breast cancer hits from Asian and European Genome Wide Association Studies in the Breast Cancer Association Consortium (BCAC)
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P50
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Professor Mayo Clinic
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Fergus J Couch
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Couch F. J.
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Fergus Couch
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Fergus J Couch
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Fergus J Couch
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Fergus J. Couch
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P106
P21
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P496
0000-0001-9417-9985