about
Recruitment of Tat to heterochromatin protein HP1 via interaction with CTIP2 inhibits human immunodeficiency virus type 1 replication in microglial cellsInhibition of microglia activation as a phenotypic assay in early drug discoveryClass I PI3K inhibitor ZSTK474 mediates a shift in microglial/macrophage phenotype and inhibits inflammatory response in mice with cerebral ischemia/reperfusion injury.Depletion of microglia and inhibition of exosome synthesis halt tau propagation.LRRK2 G2019S mutation attenuates microglial motility by inhibiting focal adhesion kinase.Estrogen ameliorates microglial activation by inhibiting the Kir2.1 inward-rectifier K(+) channel.Attenuation of astrogliosis by suppressing of microglial proliferation with the cell cycle inhibitor olomoucine in rat spinal cord injury model.Inhibition of nitric oxide synthase expression in activated microglia and peroxynitrite scavenging activity by Opuntia ficus indica var. sabotenInhibition of Alzheimer's beta-amyloid induced vasoactivity and proinflammatory response in microglia by a cGMP-dependent mechanismPropofol protects against focal cerebral ischemia via inhibition of microglia-mediated proinflammatory cytokines in a rat model of experimental strokeMicroglial CD33-related Siglec-E inhibits neurotoxicity by preventing the phagocytosis-associated oxidative burstDuloxetine Inhibits Microglial P2X4 Receptor Function and Alleviates Neuropathic Pain after Peripheral Nerve InjuryDexamethasone suppresses monocyte chemoattractant protein-1 production via mitogen activated protein kinase phosphatase-1 dependent inhibition of Jun N-terminal kinase and p38 mitogen-activated protein kinase in activated rat microgliaInhibition of neuronal nitric oxide synthase antagonizes morphine antinociceptive tolerance by decreasing activation of p38 MAPK in the spinal microgliaMinocycline down-regulates MHC II expression in microglia and macrophages through inhibition of IRF-1 and protein kinase C (PKC)alpha/betaIIEstrogen or estrogen receptor agonist inhibits lipopolysaccharide induced microglial activation and deathInhibition of brain ischemia-caused notch activation in microglia may contribute to isoflurane postconditioning-induced neuroprotection in male rats.Morphine inhibits human microglial cell production of, and migration towards, RANTES.CD45RB is a novel molecular therapeutic target to inhibit Abeta peptide-induced microglial MAPK activation.Aldose reductase inhibition prevents endotoxin-induced inflammatory responses in retinal microglia.Therapeutic inhibition of soluble brain TNF promotes remyelination by increasing myelin phagocytosis by microgliaCannabinoids Delta(9)-tetrahydrocannabinol and cannabidiol differentially inhibit the lipopolysaccharide-activated NF-kappaB and interferon-beta/STAT proinflammatory pathways in BV-2 microglial cellsQingkailing Suppresses the Activation of BV2 Microglial Cells by Inhibiting Hypoxia/Reoxygenation-Induced Inflammatory Responses.Tetracyclines inhibit microglial activation and are neuroprotective in global brain ischemiaCilostazol is anti-inflammatory in BV2 microglial cells by inactivating nuclear factor-kappaB and inhibiting mitogen-activated protein kinases.RAGE inhibition in microglia prevents ischemia-dependent synaptic dysfunction in an amyloid-enriched environmentColony stimulating factor 1 receptor inhibition eliminates microglia and attenuates brain injury after intracerebral hemorrhage.Ibudilast, a pharmacologic phosphodiesterase inhibitor, prevents human immunodeficiency virus-1 Tat-mediated activation of microglial cellsNaloxone protects rat dopaminergic neurons against inflammatory damage through inhibition of microglia activation and superoxide generation.Minocycline inhibits the production of the precursor form of nerve growth factor by retinal microglial cells.Inhibition of inflammatory mediator release from microglia can treat ischemic/hypoxic brain injuryLow-level laser light therapy improves cognitive deficits and inhibits microglial activation after controlled cortical impact in micemTOR signaling inhibition modulates macrophage/microglia-mediated neuroinflammation and secondary injury via regulatory T cells after focal ischemia.Mesenchymal stem cells inhibit lipopolysaccharide-induced inflammatory responses of BV2 microglial cells through TSG-6.Zaprinast, an inhibitor of cGMP-selective phosphodiesterases, enhances the secretion of TNF-alpha and IL-1beta and the expression of iNOS and MHC class II molecules in rat microglial cells.Inhibition by naloxone stereoisomers of beta-amyloid peptide (1-42)-induced superoxide production in microglia and degeneration of cortical and mesencephalic neurons.SCM-198 inhibits microglial overactivation and attenuates Aβ(1-40)-induced cognitive impairments in rats via JNK and NF-кB pathways.Primary murine microglia are resistant to nitric oxide inhibition of indoleamine 2,3-dioxygenase.Sevoflurane preconditioning ameliorates neuronal deficits by inhibiting microglial MMP-9 expression after spinal cord ischemia/reperfusion in ratsResveratrol inhibits inflammatory responses via the mammalian target of rapamycin signaling pathway in cultured LPS-stimulated microglial cells.
P921
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P921
description
category of moleculs that inhib the activity of microglias
@en
name
microglial inhibitor
@en
type
label
microglial inhibitor
@en
altLabel
microglia inhibition
@en
microglial Inhibitory effect
@en
prefLabel
microglial inhibitor
@en