about
Increased N-glycosylation efficiency by generation of an aromatic sequon on N135 of antithrombinAmelioration of the severity of heparin-binding antithrombin mutations by posttranslational mosaicism.Conformational activation of antithrombin by heparin involves an altered exosite interaction with protease.Identification of antithrombin-modulating genes. Role of LARGE, a gene encoding a bifunctional glycosyltransferase, in the secretion of proteins?Role of the C-sheet in the maturation of N-glycans on antithrombin: functional relevance of pleiotropic mutations.N-linked glycans within the A2 domain of von Willebrand factor modulate macrophage-mediated clearance.N-linked glycan truncation causes enhanced clearance of plasma-derived von Willebrand factor.The infective polymerization of conformationally unstable antithrombin mutants may play a role in the clinical severity of antithrombin deficiency.Disease-causing mutations in the serpin antithrombin reveal a key domain critical for inhibiting protease activities.Specific and non-overlapping functions of testosterone and 11-ketotestosterone in the regulation of professional phagocyte responses in the teleost fish gilthead seabream.Novel insights into the clinical phenotype and pathophysiology underlying low VWF levels.A novel role for the macrophage galactose-type lectin (MGL) receptor in mediating von Willebrand factor clearance.Antithrombin Dublin (p.Val30Glu): a relatively common variant with moderate thrombosis risk of causing transient antithrombin deficiency.Significant gynecological bleeding in women with low von Willebrand factor levelsA new method to quantify β-antithrombin glycoform in plasma reveals increased levels during the acute stroke eventCompound heterozygosity involving Antithrombin Cambridge II (p.Ala416Ser) in antithrombin deficiencyRegulatory regions of SERPINC1 gene: Identification of the first mutation associated with antithrombin deficiencyNovel therapies for hemophilia A - the role of the von Willebrand factor chaperonePlatelet activation and neutrophil extracellular trap (NET) formation in immune thrombocytopenia: is there an association?Increased galactose expression and enhanced clearance in patients with low von Willebrand factorTNF-α-driven inflammation and mitochondrial dysfunction define the platelet hyperreactivity of aging
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P50
description
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Sonia Aguila
@ast
Sonia Aguila
@en
Sonia Aguila
@es
Sonia Aguila
@nl
type
label
Sonia Aguila
@ast
Sonia Aguila
@en
Sonia Aguila
@es
Sonia Aguila
@nl
prefLabel
Sonia Aguila
@ast
Sonia Aguila
@en
Sonia Aguila
@es
Sonia Aguila
@nl
P106
P31
P496
0000-0001-5794-5177