about
Three-dimensional structures of the three human class I alcohol dehydrogenasesAlda-1 is an agonist and chemical chaperone for the common human aldehyde dehydrogenase 2 variantDiscovery of a Novel Class of Covalent Inhibitor for Aldehyde DehydrogenasesCatalytic contribution of threonine 244 in human ALDH2Homology-guided mutational analysis reveals the functional requirements for antinociceptive specificity of collapsin response mediator protein 2-derived peptides.A single structurally conserved SUMOylation site in CRMP2 controls NaV1.7 function.(S)-Lacosamide Binding to Collapsin Response Mediator Protein 2 (CRMP2) Regulates CaV2.2 Activity by Subverting Its Phosphorylation by Cdk5.Chemical shift perturbation mapping of the Ubc9-CRMP2 interface identifies a pocket in CRMP2 amenable for allosteric modulation of Nav1.7 channelsA Chemical Biology Approach to Model Pontocerebellar Hypoplasia Type 1B (PCH1B).Light chain C-terminal region reinforces the stability of clathrin heavy chain trimersInhibition of the Ubc9 E2 SUMO-conjugating enzyme-CRMP2 interaction decreases NaV1.7 currents and reverses experimental neuropathic painThe Natural Flavonoid Naringenin Elicits Analgesia through Inhibition of NaV1.8 Voltage-Gated Sodium ChannelsTargeting the CaVα-CaVβ interaction yields an antagonist of the N-type CaV2.2 channel with broad antinociceptive efficacySmall Molecule Targeting TDP-43's RNA Recognition Motifs Reduces Locomotor Defects in a Drosophila Model of Amyotrophic Lateral Sclerosis (ALS)
P50
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P50
description
Forscher
@de
chercheur
@fr
investigador
@es
researcher
@en
ricercatore
@it
wetenschapper
@nl
研究者
@zh
name
Samantha Perez-Miller
@ast
Samantha Perez-Miller
@en
Samantha Perez-Miller
@es
Samantha Perez-Miller
@nl
type
label
Samantha Perez-Miller
@ast
Samantha Perez-Miller
@en
Samantha Perez-Miller
@es
Samantha Perez-Miller
@nl
prefLabel
Samantha Perez-Miller
@ast
Samantha Perez-Miller
@en
Samantha Perez-Miller
@es
Samantha Perez-Miller
@nl
P31
P496
0000-0002-9034-3693