sameAs
The lipid phosphatase activity of PTEN is critical for its tumor supressor functionLinkage, association, and gene-expression analyses identify CNTNAP2 as an autism-susceptibility geneP-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphataseDBC2, a candidate for a tumor suppressor gene involved in breast cancer.Strong association of de novo copy number mutations with autismIdentification and validation of oncogenes in liver cancer using an integrative oncogenomic approachA unified genetic theory for sporadic and inherited autismThe Ras-Byr2RBD complex: structural basis for Ras effector recognition in yeastDifferential activation of yeast adenylate cyclase by wild-type and mutant RAS proteins.SCH9, a gene of Saccharomyces cerevisiae that encodes a protein distinct from, but functionally and structurally related to, cAMP-dependent protein kinase catalytic subunits.Cloning and characterization of the high-affinity cAMP phosphodiesterase of Saccharomyces cerevisiae.Cloning and characterization of BCY1, a locus encoding a regulatory subunit of the cyclic AMP-dependent protein kinase in Saccharomyces cerevisiae.DNA sequence and characterization of the S. cerevisiae gene encoding adenylate cyclase.Three different genes in S. cerevisiae encode the catalytic subunits of the cAMP-dependent protein kinase.Mutations in the SHR5 gene of Saccharomyces cerevisiae suppress Ras function and block membrane attachment and palmitoylation of Ras proteins.Representational oligonucleotide microarray analysis: a high-resolution method to detect genome copy number variationThe contribution of de novo coding mutations to autism spectrum disorderIsolation and preliminary characterization of the transforming gene of a human neuroblastoma cell lineLow load for disruptive mutations in autism genes and their biased transmissionStructure and activation of the human N-ras geneLarge-scale copy number polymorphism in the human genomeIsolation and characterization of a new cellular oncogene encoding a protein with multiple potential transmembrane domainsDLC1 is a chromosome 8p tumor suppressor whose loss promotes hepatocellular carcinomaTumour evolution inferred by single-cell sequencingInferring tumor progression from genomic heterogeneityRare De Novo and Transmitted Copy-Number Variation in Autistic Spectrum DisordersDe Novo Gene Disruptions in Children on the Autistic SpectrumCircular binary segmentation for the analysis of array-based DNA copy number dataGenome-wide copy number analysis of single cells.Accurate de novo and transmitted indel detection in exome-capture data using microassembly.SNC1, a yeast homolog of the synaptic vesicle-associated membrane protein/synaptobrevin gene family: genetic interactions with the RAS and CAP genes.Validation of S. pombe sequence assembly by microarray hybridization.Functional identification of tumor-suppressor genes through an in vivo RNA interference screen in a mouse lymphoma modelMeasuring shared variants in cohorts of discordant siblings with applications to autismIntroduction and expression of a rabbit beta-globin gene in mouse fibroblasts.Rapid phenotypic and genomic change in response to therapeutic pressure in prostate cancer inferred by high content analysis of single circulating tumor cellsTransfer of purified herpes virus thymidine kinase gene to cultured mouse cells.Transformation of mammalian cells with genes from procaryotes and eucaryotes.DNA-mediated transfer of the adenine phosphoribosyltransferase locus into mammalian cellsReducing system noise in copy number data using principal components of self-self hybridizations
P50
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P50
description
American molecular biologist
@en
Amerikaans moleculair bioloog
@nl
US-amerikanischer Biochemiker und Genetiker
@de
bitheolaí móilíneach Meiriceánach
@ga
name
Michael H. Wigler
@de
Michael Wigler
@ast
Michael Wigler
@ca
Michael Wigler
@en
Michael Wigler
@es
Michael Wigler
@fr
Michael Wigler
@ga
Michael Wigler
@it
Michael Wigler
@nl
Michael Wigler
@sl
type
label
Michael H. Wigler
@de
Michael Wigler
@ast
Michael Wigler
@ca
Michael Wigler
@en
Michael Wigler
@es
Michael Wigler
@fr
Michael Wigler
@ga
Michael Wigler
@it
Michael Wigler
@nl
Michael Wigler
@sl
prefLabel
Michael H. Wigler
@de
Michael Wigler
@ast
Michael Wigler
@ca
Michael Wigler
@en
Michael Wigler
@es
Michael Wigler
@fr
Michael Wigler
@ga
Michael Wigler
@it
Michael Wigler
@nl
Michael Wigler
@sl
P106
P214
P244
P1153
7005241418
P21
P213
0000 0000 8464 6757
P214
P2381
P244
P31
P496
0000-0003-4396-1971
P569
1947-09-03T00:00:00Z
P735
P7859
lccn-n86850971