about
Acetylation-dependent regulation of MDM2 E3 ligase activity dictates its oncogenic function.The SCFβ-TRCP E3 ubiquitin ligase complex targets Lipin1 for ubiquitination and degradation to promote hepatic lipogenesis.The mTOR-S6K pathway links growth signalling to DNA damage response by targeting RNF168.Skp2-dependent reactivation of AKT drives resistance to PI3K inhibitors.Mutually exclusive acetylation and ubiquitylation of the splicing factor SRSF5 control tumor growth.SCF-mediated degradation of Brg1 suppresses gastric cancer metastasisK63-linked polyubiquitin chains bind to DNA to facilitate DNA damage repair.AKT methylation by SETDB1 promotes AKT kinase activity and oncogenic functionsLATS suppresses mTORC1 activity to directly coordinate Hippo and mTORC1 pathways in growth controlLight-induced control of protein destruction by opto-PROTACThe role of ubiquitination in tumorigenesis and targeted drug discoveryDegrading proteins in animals: "PROTAC"tion goes in vivoReactivation of PTEN tumor suppressor for cancer treatment through inhibition of a MYC-WWP1 inhibitory pathwayDUB-independent regulation of pVHL by OTUD6B suppresses hepatocellular carcinomaThe CRL3BTBD9 E3 ubiquitin ligase complex targets TNFAIP1 for degradation to suppress cancer cell migrationThe diverse roles of SPOP in prostate cancer and kidney cancer
P50
Q33791305-12A491EF-35A0-4AEF-A393-3A3215673486Q37562004-258C04D7-DEDF-4F6F-B5C7-46A904235EA5Q48102770-97E0B4FF-3BDA-403B-AECC-DD0A3885C5FFQ52356988-E1B96C9C-94F2-42F0-B7E6-3F6EFD50268CQ55315704-C24F3C25-2180-4BA7-B353-E82181D40290Q57753119-6F836753-7E72-4250-9D44-370F1BBEE611Q64885990-4252FAEA-D664-42E1-B8FB-539FF666D237Q68692596-6D01F192-8A19-444B-B271-BFB73F1FB9FFQ89518745-209A9DD6-B995-463B-9411-91231128B595Q90017092-662BE6A7-E47D-4263-B68B-7BB3C85BFE15Q90093670-FC06D6C5-877D-4CB7-A3BF-CBDCF203A8A1Q91636999-0693ECFB-E749-4DB6-BE36-DAB9FE5F24EAQ92090098-E6196DC0-CB62-4011-9FEC-AB00E64A83EFQ93170018-0971AC46-595E-463A-A3B6-A767B18E3708Q93195753-5B32A528-BD85-44FB-8633-5B0D899CE982Q94474488-5E2AB144-A000-47AD-9376-3CE3CC854CED
P50
description
Forscher
@de
chercheur
@fr
investigador
@es
researcher
@en
ricercatore
@it
wetenschapper
@nl
研究者
@zh
name
Wenyi Wei
@ast
Wenyi Wei
@en
Wenyi Wei
@es
Wenyi Wei
@nl
type
label
Wenyi Wei
@ast
Wenyi Wei
@en
Wenyi Wei
@es
Wenyi Wei
@nl
prefLabel
Wenyi Wei
@ast
Wenyi Wei
@en
Wenyi Wei
@es
Wenyi Wei
@nl
P31
P496
0000-0003-0512-3811