about
Constitutive and interleukin-1-inducible phosphorylation of p65 NF-{kappa}B at serine 536 is mediated by multiple protein kinases including I{kappa}B kinase (IKK)-{alpha}, IKK{beta}, IKK{epsilon}, TRAF family member-associated (TANK)-binding kinaseNF-kappaB: a multifaceted transcription factor regulated at several levelsThe 73 kDa subunit of the CPSF complex binds to the HIV-1 LTR promoter and functions as a negative regulatory factor that is inhibited by the HIV-1 Tat protein.Mutations of c-Cbl in myeloid malignanciesIntegration of the activation of the human hyaluronan synthase 2 gene promoter by common cofactors of the transcription factors retinoic acid receptor and nuclear factor kappaB.Phosphorylation-dependent control of Pc2 SUMO E3 ligase activity by its substrate protein HIPK2.Role of CREB1 and NF{kappa}B-p65 in the down-regulation of renin gene expression by tumor necrosis factor {alpha}.Hypericin as a non-antioxidant inhibitor of NF-kappa B.From top to bottom: the two faces of HIPK2 for regulation of the hypoxic response.Inducible phosphorylation of NF-kappa B p65 at serine 468 by T cell costimulation is mediated by IKK epsilon.NF-κB p65 serine 467 phosphorylation sensitizes mice to weight gain and TNFα-or diet-induced inflammation.Testing the Effects of SIAH Ubiquitin E3 Ligases on Lysine Acetyl Transferases.T cell receptor-induced lipid raft recruitment of the I kappa B kinase complex is necessary and sufficient for NF-kappa B activation occurring in the cytosol.Critical role of NF-kappaB and stress-activated protein kinases in steroid unresponsiveness.RNAi-Based Identification of Gene-Specific Nuclear Cofactor Networks Regulating Interleukin-1 Target Genes.IL-17 reduces TNF-induced Rantes and VCAM-1 expressionInhibition of NF-κB activation and expression of inflammatory mediators by polyacetylene spiroketals from Plagius flosculosusCDK1-mediated phosphorylation at H2B serine 6 is required for mitotic chromosome segregationInhibition of tyrosine phosphatases induces apoptosis independent from the CD95 systemCaspase-dependent cleavage and inactivation of the Vav1 proto-oncogene product during apoptosis prevents IL-2 transcriptionPheophorbide A from Solanum diflorum interferes with NF-kappa B activationSynergistic activation of NF-kappa B by functional cooperation between vav and PKCtheta in T lymphocytesCD95-induced JNK activation signals are transmitted by the death-inducing signaling complex (DISC), but not by DaxxRepression of NF-kappaB impairs HeLa cell proliferation by functional interference with cell cycle checkpoint regulatorsThe promoter context determines mutual repression or synergism between NF-kappaB and the glucocorticoid receptorOf mice and menComparative analysis of T-cell costimulation and CD43 activation reveals novel signaling pathways and target genesNF-κB p65 dimerization and DNA-binding is important for inflammatory gene expressionDistinct IL-1α-responsive enhancers promote acute and coordinated changes in chromatin topology in a hierarchical mannerDifferential intracellular localization and dynamic nucleocytoplasmic shuttling of homeodomain-interacting protein kinase family membersSingle-Cell Analysis of Multiple Steps of Dynamic NF-κB Regulation in Interleukin-1α-Triggered Tumor Cells Using Proximity Ligation AssaysULK1/2 Restricts the Formation of Inducible SINT-Speckles, Membraneless Organelles Controlling the Threshold of TBK1 ActivationPriming chromatin for segregation: functional roles of mitotic histone modificationsChemotherapeutic Drugs Inhibiting Topoisomerase 1 Activity Impede Cytokine-Induced and NF-κB p65-Regulated Gene ExpressionPhosphoproteome Analysis of Cells Infected with Adapted and Nonadapted Influenza A Virus Reveals Novel Pro- and Antiviral Signaling Networks
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P50
description
researcher
@en
name
M. Lienhard Schmitz
@en
Schmitz ML
@nl
type
label
M. Lienhard Schmitz
@en
Schmitz ML
@nl
altLabel
Schmitz ML
@en
prefLabel
M. Lienhard Schmitz
@en
Schmitz ML
@nl
P106
P31
P496
0000-0002-6984-7192