about
Synthesis and stereochemical determination of an antiparasitic pseudo-aminal type monoterpene indole alkaloidParallel and four-step synthesis of natural-product-inspired scaffolds through modular assembly and divergent cyclization.Selective and potent in vitro antitrypanosomal activities of ten microbial metabolites.In vitro and in vivo antitrypanosomal activitiy of two microbial metabolites, KS-505a and alazopeptin.In vitro and in vivo antitrypanosomal activities of three peptide antibiotics: leucinostatin A and B, alamethicin I and tsushimycin.Generation of anti-trypanosomal agents through concise synthesis and structural diversification of sesquiterpene analogues.The first total synthesis of (+/-)-arisugacin A, a potent, orally bioavailable inhibitor of acetylcholinesterase.Clofazimine Inhibits the Growth of Babesia and Theileria Parasites In Vitro and In Vivo.Semisynthesis of salviandulin E analogues and their antitrypanosomal activity.Antimalarial activity of kinase inhibitor, nilotinib, in vitro and in vivo.Satoshi Omura: in pursuit of nature's bounty.Panowamycins A and B, new antitrypanosomal isochromans produced by Streptomyces sp. K07-0010.Actinoallolides A-E, new anti-trypanosomal macrolides, produced by an endophytic actinomycete, Actinoallomurus fulvus MK10-036.Antimalarial tropones and their Plasmodium falciparum glyoxalase I (pfGLOI) inhibitory activity.In vitro antitrypanosomal activity of five low-MW antibiotics.Borrelidin, a potent antimalarial: stage-specific inhibition profile of synchronized cultures of Plasmodium falciparum.Jogyamycin, a new antiprotozoal aminocyclopentitol antibiotic, produced by Streptomyces sp. a-WM-JG-16.2.In vitro and in vivo antimalarial activity of puberulic acid and its new analogs, viticolins A-C, produced by Penicillium sp. FKI-4410.In vitro antitrypanosomal activity of 12 low-molecular-weight antibiotics and observations of structure/activity relationships.Antitrypanosomal peptaibiotics, trichosporins B-VIIa and B-VIIb, produced by Trichoderma polysporum FKI-4452.Borrelidin analogues with antimalarial activity: design, synthesis and biological evaluation against Plasmodium falciparum parasites.Sinefungin VA and dehydrosinefungin V, new antitrypanosomal antibiotics produced by Streptomyces sp. K05-0178.Isolation and Total Synthesis of Hoshinolactam, an Antitrypanosomal Lactam from a Marine Cyanobacterium.In vitro antitrypanosomal activity of some phenolic compounds from propolis and lactones from Fijian Kawa (Piper methysticum).In vitro antitrypanosomal activity of bis(bibenzyls)s and bibenzyls from liverworts against Trypanosoma brucei.In vitro antitrypanosomal activity of plant terpenes against Trypanosoma brucei.Promising lead compounds for novel antiprotozoals.Spoxazomicins A-C, novel antitrypanosomal alkaloids produced by an endophytic actinomycete, Streptosporangium oxazolinicum K07-0460(T).In Vitro Antitrypanosomal Activity of the Secondary Metabolites from the Mutant Strain IU-3 of the Insect Pathogenic Fungus Ophiocordyceps coccidiicola NBRC 100683.Antitrypanosomal activity of some pregnane glycosides isolated from Caralluma species.Antiplasmodial and antitrypanosomal activity of plants from the Kingdom of Saudi Arabia.Acylated pregnane glycosides from Caralluma tuberculata and their antiparasitic activity.In vitro antimalarial activity of prenylated flavonoids from Erythrina fusca.Antimalarial troponoids, puberulic acid and viticolins; divergent synthesis and structure-activity relationship studies.Remarkable influence of the aromatic substructure in 9-methoxystrobilurin derivatives on their antifungal activity.Anti-trypanosomal compound, sagamilactam, a new polyene macrocyclic lactam from Actinomadura sp. K13-0306.Asymmetric Total Synthesis of Indole Alkaloids Containing an Indoline Spiroaminal Framework.In vitro antimalarial activity of biflavonoids from Wikstroemia indica.Structure determination and total synthesis of (+)-16-hydroxy-16,22-dihydroapparicine.Antimalarial C-9 oxime derivatives from desmycosin, produced by click chemistry.
P50
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P50
name
Kazuhiko Otoguro
@en
Kazuhiko Otoguro
@nl
type
label
Kazuhiko Otoguro
@en
Kazuhiko Otoguro
@nl
prefLabel
Kazuhiko Otoguro
@en
Kazuhiko Otoguro
@nl