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Downstream processing from hot-melt extrusion towards tablets: A quality by design approach.Thermoplastic polyurethane-based intravaginal rings for prophylaxis and treatment of (recurrent) bacterial vaginosis.Multivariate statistical process control of a continuous pharmaceutical twin-screw granulation and fluid bed drying process.Linking granulation performance with residence time and granulation liquid distributions in twin-screw granulation: An experimental investigation.Conceptual framework for model-based analysis of residence time distribution in twin-screw granulation.3D printing of high drug loaded dosage forms using thermoplastic polyurethanes.Downstream processing from melt granulation towards tablets: In-depth analysis of a continuous twin-screw melt granulation process using polymeric binders.Novel self-gelling injectable hydrogel/alpha-tricalcium phosphate composites for bone regeneration: Physiochemical and microcomputer tomographical characterization.Breakage and drying behaviour of granules in a continuous fluid bed dryer: Influence of process parameters and wet granule transfer.The relevance of shear, sedimentation and diffusion during spin freezing, as potential first step of a continuous freeze-drying process for unit doses.Raw material variability of an active pharmaceutical ingredient and its relevance for processability in secondary continuous pharmaceutical manufacturing.Development and validation of an in-line NIR spectroscopic method for continuous blend potency determination in the feed frame of a tablet press.Lubricant sensitivity in function of paddle movement in the forced feeder of a high-speed tablet press.Improved tabletability after a polymorphic transition of delta-mannitol during twin screw granulation.Mixing and transport during pharmaceutical twin-screw wet granulation: experimental analysis via chemical imaging.Continuous manufacturing of delta mannitol by cospray drying with PVP.Development of a continuous direct compression platform for low-dose drug products.The use of partially hydrolysed polyvinyl alcohol for the production of high drug-loaded sustained release pellets via extrusion-spheronisation and coating: In vitro and in vivo evaluation.Humans significantly metabolize and excrete the mycotoxin deoxynivalenol and its modified form deoxynivalenol-3-glucoside within 24 hours.Novel injectable gellan gum hydrogel composites incorporating Zn- and Sr-enriched bioactive glass microparticles: High-resolution X-ray microcomputed tomography, antibacterial and in vitro testing.A multivariate raw material property database to facilitate drug product development and enable in-silico design of pharmaceutical dry powder processesImpact of blend properties on die filling during tabletingDownscaling of the tableting process: Feasibility of miniaturized forced feeders on a high-speed rotary tablet pressPectin-bioactive glass self-gelling, injectable composites with high antibacterial activityModeling of Semicontinuous Fluid Bed Drying of Pharmaceutical Granules With Respect to Granule SizeCrystal coating via spray drying to improve powder tabletabilityOptimizing feed frame design and tableting process parameters to increase die-filling uniformity on a high-speed rotary tablet pressImpact of material properties and process variables on the residence time distribution in twin screw feeding equipmentManaging active pharmaceutical ingredient raw material variability during twin-screw blend feedingNative starch as in situ binder for continuous twin screw wet granulationA multivariate approach to predict the volumetric and gravimetric feeding behavior of a low feed rate feeder based on raw material propertiesEvaluation of an in-line NIR spectroscopic method for the determination of the residence time in a tablet pressManaging API raw material variability in a continuous manufacturing line - Prediction of process robustnessManaging API raw material variability during continuous twin-screw wet granulationPharmaceutical compounding of orphan active ingredients in Belgium: how community and hospital pharmacists can address the needs of patients with rare diseases
P50
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P50
description
investigador
@es
researcher
@en
wetenschapper
@nl
name
V Vanhoorne
@en
V Vanhoorne
@nl
type
label
V Vanhoorne
@en
V Vanhoorne
@nl
prefLabel
V Vanhoorne
@en
V Vanhoorne
@nl
P31
P496
0000-0003-4249-3408