about
A mutation in the translation initiation codon of Gata-1 disrupts megakaryocyte maturation and causes thrombocytopenia.Characterization of thrombopoietin (TPO)-responsive progenitor cells in adult mouse bone marrow with in vivo megakaryocyte and erythroid potentialSuppressor screen in Mpl-/- mice: c-Myb mutation causes supraphysiological production of platelets in the absence of thrombopoietin signaling.Polycystic kidneys and chronic inflammatory lesions are the delayed consequences of loss of the suppressor of cytokine signaling-1 (SOCS-1).Multipotential hematopoietic blast colony-forming cells exhibit delays in self-generation and lineage commitment.Crowding-dependent production of colony-stimulating factors by cultured syngeneic or allogeneic hematopoietic cellsInactivation of PU.1 in adult mice leads to the development of myeloid leukemiaThe lethal effects of transplantation of Socs1-/- bone marrow cells into irradiated adult syngeneic recipientsEarly lineage priming by trisomy of Erg leads to myeloproliferation in a Down syndrome model.Clonogenic mast cell progenitors and their excess numbers in chimeric BALB/c mice with inactivated GATA-1Hematopoietic overexpression of the transcription factor Erg induces lymphoid and erythro-megakaryocytic leukemia.The preleukemic state of mice reconstituted with Mixl1-transduced marrow cellsPU.1 regulates the commitment of adult hematopoietic progenitors and restricts granulopoiesisConcordant mast cell and basophil production by individual hematopoietic blast colony-forming cells.Reversible growth factor dependency and autonomy during murine myelomonocytic leukemia induced by oncogenes.Mpl expression on megakaryocytes and platelets is dispensable for thrombopoiesis but essential to prevent myeloproliferation.Stem cell factor can stimulate the formation of eosinophils by two types of murine eosinophil progenitor cells.The BH3-only proteins BIM and PUMA are not critical for the reticulocyte apoptosis caused by loss of the pro-survival protein BCL-XL.Murine hematopoietic blast colony-forming cells and their progeny have distinctive membrane marker profiles.Hhex Regulates Hematopoietic Stem Cell Self-Renewal and Stress Hematopoiesis via Repression of Cdkn2a.RIPK1 regulates RIPK3-MLKL-driven systemic inflammation and emergency hematopoiesis.Trisomy of Erg is required for myeloproliferation in a mouse model of Down syndromeSynergistic and inhibitory interactions in the in vitro control of murine megakaryocyte colony formationMurine megakaryocyte progenitor cells and their susceptibility to suppression by G-CSF
P50
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P50
name
Ladina Di Rago
@en
type
label
Ladina Di Rago
@en
prefLabel
Ladina Di Rago
@en