about
Kempopeptin C, a Novel Marine-Derived Serine Protease Inhibitor Targeting Invasive Breast Cancer.Apratyramide, a Marine-Derived Peptidic Stimulator of VEGF-A and Other Growth Factors with Potential Application in Wound Healing.Grassystatins D-F, Potent Aspartic Protease Inhibitors from Marine Cyanobacteria as Potential Antimetastatic Agents Targeting Invasive Breast Cancer.Correction to Apratoxin E, a Cytotoxic Peptolide from a Guamanian Collection of the Marine Cyanobacterium Lyngbya bouillonii.Photosynthetic Production of Sunscreen Shinorine Using an Engineered Cyanobacterium.Rational engineering of Streptomyces albus J1074 for the overexpression of secondary metabolite gene clusters.Structural Diversity and Anticancer Activity of Marine-Derived Elastase Inhibitors: Key Features and Mechanisms Mediating the Antimetastatic Effects in Invasive Breast Cancer.A Complementary Chemical and Genomic Screening Approach for Druggable Targets in the Nrf2 Pathway and Small Molecule Inhibitors to Overcome Cancer Cell Drug Resistance.An Efficient Buchwald-Hartwig/Reductive Cyclization for the Scaffold Diversification of Halogenated Phenazines: Potent Antibacterial Targeting, Biofilm Eradication, and Prodrug Exploration.Total Synthesis of Asperphenins A and BChemical and Metagenomic Studies of the Lethal Black Band Disease of Corals Reveal Two Broadly Distributed, Redox-Sensitive Mixed Polyketide/Peptide MacrocyclesIsolation, Structure Elucidation and Biological Evaluation of Lagunamide D: A New Cytotoxic Macrocyclic Depsipeptide from Marine CyanobacteriaNatural products as modulators of eukaryotic protein secretionDiscovery, Synthesis, Pharmacological Profiling, and Biological Characterization of Brintonamides A-E, Novel Dual Protease and GPCR Modulators from a Marine CyanobacteriumDevelopment of apratoxin S10 (Apra S10) as an anti-pancreatic cancer agent and its preliminary evaluation in an orthotopic patient-derived xenograft (PDX) modelDiscovery of Amantamide, a Selective CXCR7 Agonist from Marine CyanobacteriaPreventing Morphine-Seeking Behavior through the Re-Engineering of Vincamine's Biological ActivityTutuilamides A-C: Vinyl-Chloride-Containing Cyclodepsipeptides from Marine Cyanobacteria with Potent Elastase Inhibitory PropertiesDiscovery and Total Synthesis of Doscadenamide A: A Quorum Sensing Signaling Molecule from a Marine CyanobacteriumNew methods for isolation and structure determination of natural productsIsolation and Characterization of Anaephenes A-C, Alkylphenols from a Filamentous Cyanobacterium ( Hormoscilla sp., Oscillatoriales)Discovery, Total Synthesis, and SAR of Anaenamides A and B: Anticancer Cyanobacterial Depsipeptides with a Chlorinated PharmacophoreTargeting eukaryotic proteases for natural products-based drug developmentTargeting and extending the eukaryotic druggable genome with natural productsLargazole is a Brain-Penetrant Class I HDAC Inhibitor with Extended Applicability to Glioblastoma and CNS Diseases
P50
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P50
description
researcher
@en
name
Hendrik Luesch
@en
Hendrik Luesch
@pt
Hendrik Luesch
@pt-br
type
label
Hendrik Luesch
@en
Hendrik Luesch
@pt
Hendrik Luesch
@pt-br
prefLabel
Hendrik Luesch
@en
Hendrik Luesch
@pt
Hendrik Luesch
@pt-br
P1153
6603594403
P21
P31
P496
0000-0002-4091-7492