about
Lectin-dependent enhancement of Ebola virus infection via soluble and transmembrane C-type lectin receptorsTIM-family proteins promote infection of multiple enveloped viruses through virion-associated phosphatidylserineIFITM proteins restrict antibody-dependent enhancement of dengue virus infectionInfluenza A virus NS1 targets the ubiquitin ligase TRIM25 to evade recognition by the host viral RNA sensor RIG-IUVRAG is required for virus entry through combinatorial interaction with the class C-Vps complex and SNAREsDistinct patterns of IFITM-mediated restriction of filoviruses, SARS coronavirus, and influenza A virusACE2 receptor expression and severe acute respiratory syndrome coronavirus infection depend on differentiation of human airway epithelia.The IFITM proteins mediate cellular resistance to influenza A H1N1 virus, West Nile virus, and dengue virusInfluenza A virus neuraminidase limits viral superinfectionThe interferon-stimulated gene IFITM3 restricts West Nile virus infection and pathogenesisIfitm3 limits the severity of acute influenza in miceHost-Species Transferrin Receptor 1 Orthologs Are Cellular Receptors for Nonpathogenic New World Clade B ArenavirusesStructural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120Structural basis for receptor recognition by New World hemorrhagic fever arenavirusesAngiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirusA 193-amino acid fragment of the SARS coronavirus S protein efficiently binds angiotensin-converting enzyme 2Infection of human airway epithelia by SARS coronavirus is associated with ACE2 expression and localizationDual host-virus arms races shape an essential housekeeping proteinEvolution of a TRIM5-CypA splice isoform in old world monkeysStructural basis of neutralization by a human anti-severe acute respiratory syndrome spike protein antibody, 80R.Engineering antibody-like inhibitors to prevent and treat HIV-1 infection.Protein evolution with an expanded genetic codeIdentification of a new region of SARS-CoV S protein critical for viral entryThe antiviral restriction factors IFITM1, 2 and 3 do not inhibit infection of human papillomavirus, cytomegalovirus and adenovirus.Functional mimicry of a human immunodeficiency virus type 1 coreceptor by a neutralizing monoclonal antibody.Evaluation of human monoclonal antibody 80R for immunoprophylaxis of severe acute respiratory syndrome by an animal study, epitope mapping, and analysis of spike variants.Recombinant modified vaccinia virus Ankara expressing the spike glycoprotein of severe acute respiratory syndrome coronavirus induces protective neutralizing antibodies primarily targeting the receptor binding region.Mutagenesis and evolution of sulfated antibodies using an expanded genetic code.IFITM3 polymorphism rs12252-C restricts influenza A viruses.The antiviral effector IFITM3 disrupts intracellular cholesterol homeostasis to block viral entry.Increased CCR5 affinity and reduced CCR5/CD4 dependence of a neurovirulent primary human immunodeficiency virus type 1 isolate.Structure of SARS coronavirus spike receptor-binding domain complexed with receptor.AAV-expressed eCD4-Ig provides durable protection from multiple SHIV challenges.Receptor determinants of zoonotic transmission of New World hemorrhagic fever arenaviruses.Direct expression and validation of phage-selected peptide variants in mammalian cells.Conformational states of the severe acute respiratory syndrome coronavirus spike protein ectodomain.A tyrosine-sulfated CCR5-mimetic peptide promotes conformational transitions in the HIV-1 envelope glycoprotein.Ebolavirus delta-peptide immunoadhesins inhibit marburgvirus and ebolavirus cell entry.Transferrin receptor 1 is a cellular receptor for New World haemorrhagic fever arenaviruses.Neutralization properties of simian immunodeficiency viruses infecting chimpanzees and gorillas.
P50
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P50
name
Michael Farzan
@en
type
label
Michael Farzan
@en
prefLabel
Michael Farzan
@en