5-IAI
5-Iodo-2-aminoindane (5-IAI) is a drug which acts as a releasing agent of serotonin, norepinephrine, and dopamine. It was developed in the 1990s by a team led by David E. Nichols at Purdue University. 5-IAI fully substitutes for MDMA in rodents and is a putative entactogen in humans. Unlike related aminoindane derivatives like MDAI and MMAI, 5-IAI causes some serotonergic neurotoxicity in rats, but is substantially less toxic than its corresponding amphetamine homologue pIA, with the damage observed barely reaching statistical significance.
primaryTopic
5-IAI
5-Iodo-2-aminoindane (5-IAI) is a drug which acts as a releasing agent of serotonin, norepinephrine, and dopamine. It was developed in the 1990s by a team led by David E. Nichols at Purdue University. 5-IAI fully substitutes for MDMA in rodents and is a putative entactogen in humans. Unlike related aminoindane derivatives like MDAI and MMAI, 5-IAI causes some serotonergic neurotoxicity in rats, but is substantially less toxic than its corresponding amphetamine homologue pIA, with the damage observed barely reaching statistical significance.
has abstract
5-Iodo-2-aminoindane (5-IAI) i ...... hing statistical significance.
@en
5-ヨード-2-アミノインダン(5-Iodo-2-amino ...... 低く、観測される障害が統計的優位性に達することは滅多にない。
@ja
ATC prefix
CAS number
132367-76-1
FDA UNII code
7X16E45Y1X
IUPAC name
5-iodo-2,3-dihydro-1H-inden-2-amine
@en
PubChem
thumbnail
Wikipage page ID
22,626,120
Wikipage revision ID
734,541,924
ChemSpiderID
legal status
molecular weight
2.59087e+2
pregnancy category
routes of administration
smiles
c2c1CCCc1ccc2I
StdInChIKey
BIHPYCDDPGNWQO-UHFFFAOYSA-N
Verifiedfields
verifiedrevid
477,224,727
subject
hypernym
comment
5-Iodo-2-aminoindane (5-IAI) i ...... hing statistical significance.
@en
5-ヨード-2-アミノインダン(5-Iodo-2-amino ...... 低く、観測される障害が統計的優位性に達することは滅多にない。
@ja
label
5-IAI
@en
5-ヨード-2-アミノインダン
@ja