Apoptosis-inducing factor
Apoptosis inducing factor is a flavoprotein. Apoptosis inducing factor is involved in initiating a caspase-independent pathway of apoptosis (positive intrinsic regulator of apoptosis) by causing DNA fragmentation and chromatin condensation. It also acts as an NADH oxidase. Another AIF function is to regulate the permeability of the mitochondrial membrane upon apoptosis. Normally it is found behind the outer membrane of the mitochondria and is therefore secluded from the nucleus. However, when the mitochondrion is damaged, it moves to the cytosol and to the nucleus. Inactivation of AIF leads to resistance of embryonic stem cells to death following the withdrawal of growth factors indicating that it is involved in apoptosis.
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Apoptosis-inducing factor
Apoptosis inducing factor is a flavoprotein. Apoptosis inducing factor is involved in initiating a caspase-independent pathway of apoptosis (positive intrinsic regulator of apoptosis) by causing DNA fragmentation and chromatin condensation. It also acts as an NADH oxidase. Another AIF function is to regulate the permeability of the mitochondrial membrane upon apoptosis. Normally it is found behind the outer membrane of the mitochondria and is therefore secluded from the nucleus. However, when the mitochondrion is damaged, it moves to the cytosol and to the nucleus. Inactivation of AIF leads to resistance of embryonic stem cells to death following the withdrawal of growth factors indicating that it is involved in apoptosis.
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Apoptosis inducing factor is a ...... t it is involved in apoptosis.
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Czynnik indukujący apoptozę (a ...... azmy komórki podczas apoptozy.
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凋亡诱导因子(英语:Apoptosis-inducing f ...... ,当线粒体受损时,凋亡诱导因子就会移动到胞质溶胶与细胞核中。
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720,420,262
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Crystallographic structure of the human apoptosis inducing factor .
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Apoptosis inducing factor is a ...... t it is involved in apoptosis.
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Czynnik indukujący apoptozę (a ...... azmy komórki podczas apoptozy.
@pl
凋亡诱导因子(英语:Apoptosis-inducing f ...... ,当线粒体受损时,凋亡诱导因子就会移动到胞质溶胶与细胞核中。
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Apoptosis-inducing factor
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Czynnik indukujący apoptozę
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凋亡诱导因子
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apoptosis-inducing factor, mitochondrion-associated, 1
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