Bendamustine
Bendamustine (INN, trade names Treakisym, Ribomustin, Levact and Treanda; also known as SDX-105) is a nitrogen mustard used in the treatment of chronic lymphocytic leukemia and lymphomas. It belongs to the family of drugs called alkylating agents. It is also being studied for the treatment of sarcoma. It is also being investigated in phase II trials for the non-cancer treatment of AL amyloidosis. It is on the World Health Organization's List of Essential Medicines, a list of the most important medications needed in a basic health system.
primaryTopic
Bendamustine
Bendamustine (INN, trade names Treakisym, Ribomustin, Levact and Treanda; also known as SDX-105) is a nitrogen mustard used in the treatment of chronic lymphocytic leukemia and lymphomas. It belongs to the family of drugs called alkylating agents. It is also being studied for the treatment of sarcoma. It is also being investigated in phase II trials for the non-cancer treatment of AL amyloidosis. It is on the World Health Organization's List of Essential Medicines, a list of the most important medications needed in a basic health system.
has abstract
Bendamustin ist ein antitumora ...... der Bundesrepublik zugelassen.
@de
Bendamustina (nome commerciale ...... iplo e del linfoma di Hodgkin.
@it
Bendamustina o Clorhidrato de ...... para el tratamiento de sarcoma
@es
Bendamustine (INN, trade names ...... eded in a basic health system.
@en
Bendamustine is een alkylerend ...... cellen zijn hiervoor gevoelig.
@nl
Бендамустин — цитостатический ...... водным бис-бета-хлорэтиламина.
@ru
ベンダムスチン(bendamustine)は、1960年代初 ...... 売提携している。商品名はトレアキシン(Treakisym)。
@ja
ATC prefix
ATC suffix
CAS number
16506-27-7
FDA UNII code
9266D9P3PQ
IUPAC name
4-[5-[Bis(2-chloroethyl)amino]-1-methylbenzimidazol-2-yl]butanoic acid
@en
PubChem
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Link from a Wikipage to an external page
Wikipage page ID
15,390,625
Wikipage revision ID
722,176,128
bioavailability
ChEMBL
ChemSpiderID
elimination half-life
excretion
~50% urinary, ~25% fecal
IUPHAR ligand
legal US
licence US
MedlinePlus
metabolism
Hydrolyzed to inactive metabolites. Two minor metabolites formed by CYP1A2
molecular weight
3.58262e+2
protein bound
routes of administration
Intravenous infusion
smiles
StdInChIKey
YTKUWDBFDASYHO-UHFFFAOYSA-N
tradename
verifiedrevid
461,512,035
Watchedfields
hypernym
comment
Bendamustin ist ein antitumora ...... klonalen Antikörper Rituximab.
@de
Bendamustina (nome commerciale ...... iplo e del linfoma di Hodgkin.
@it
Bendamustina o Clorhidrato de ...... para el tratamiento de sarcoma
@es
Bendamustine (INN, trade names ...... eded in a basic health system.
@en
Bendamustine is een alkylerend ...... cellen zijn hiervoor gevoelig.
@nl
Бендамустин — цитостатический ...... водным бис-бета-хлорэтиламина.
@ru
ベンダムスチン(bendamustine)は、1960年代初 ...... 売提携している。商品名はトレアキシン(Treakisym)。
@ja
label
Bendamustin
@de
Bendamustina
@es
Bendamustina
@it
Bendamustine
@en
Bendamustine
@nl
Бендамустин
@ru
ベンダムスチン
@ja