The Benninghofen House is a historic residence in Hamilton, Ohio, United States. Constructed in the 1860s, this house has been named a historic site for its high-quality architecture. Once the home of prominent Hamilton residents, it has been converted into a museum. In 1973, the Benninghofen House was listed on the National Register of Historic Places, qualifying both because of its historic architecture and because of its connection to John Benninghofer. It is one of sixteen Hamilton locations on the Register, and one of more than eighty countywide.