Chalcedonian Christianity is a term referring to Christian denominations adhering to the Definition of Chalcedon (451 AD), a religious doctrine concerning the divine and human nature of Jesus Christ. While most existing Christian denominations are considered Chalcedonian, in the 5th – 8th centuries the ascendancy of Chalcedonian Christology was not always certain. Some Armenian Christians (especially in the region of Cappadocia and Trebizond inside the Byzantine Empire) did accept the decisions of the Council of Chalcedon and engaged in polemics against the Armenian Apostolic Church.