The Francis M. Drexel School was a historic school in Philadelphia, Pennsylvania, United States. Located along Sixteenth Street, the school was designed by Joseph Anschutz and built under the direction of Charles O'Neill, Jr. The three-story brick building was built in a regular rectangular plan in the Victorian style of architecture, with three chimneys dominating its facade. The school was named for Francis Martin Drexel, whose son, banker and philanthropist Anthony J. Drexel, founded Drexel University two years after the construction of the school.