The Hill to Hill Bridge is a road crossing of the Lehigh River linking the south and north sides of Bethlehem, Pennsylvania. It was completed in 1924. It carries Pennsylvania Route 378 from Wyandotte Street on the city's south side to a series of ramps and viaducts on the north side. It replaced a two-lane covered bridge and eliminated several grade crossings of three railroads on the two banks of the Lehigh River. It is located in the Central Bethlehem Historic District, listed on the National Register of Historic Places in 1972, with a Boundary Increase in 1988.