The Maryland Campaign—or Antietam Campaign—occurred September 4–20, 1862, during the American Civil War. Confederate Gen. Robert E. Lee's first invasion of the North was repulsed by the Army of the Potomac under Maj. Gen. George B. McClellan, who moved to intercept Lee and his Army of Northern Virginia and eventually attacked it near Sharpsburg, Maryland. The resulting Battle of Antietam was the bloodiest single-day battle in American history and is widely considered one of the major turning points of the war.