Shimotsuma Domain (下妻藩 Shimotsuma-han) was a feudal domain under the Tokugawa shogunate of Edo period Japan, located in Hitachi Province (modern-day Ibaraki Prefecture), Japan. It was centered on Shimotsuma Jin'ya in what is now the city of Shimotsuma, Ibaraki. It was ruled for much of its history by a junior branch of the Inoue clan; however, it suffered from frequent changes of rules due to the tendency of the Inoue daimyo to die at young ages.