The South Henderson Church is a historic Presbyterian church located in rural Henderson County, Illinois, east of the village of Gladstone. The church was built in 1854; it was the second church building used by the local Associate Reformed Presbyterian congregation, which formed in 1835 and built its first church two years later. The vernacular building has a wood frame plan and limestone walls and used local materials in its construction, which cost $3,855.55. Reverend Robert Ross led the congregation when it built the 1854 church; Ross was one of the founders of Monmouth College and served on its first Board of Trustees.