The Squire Chase House is a historic house on Main Street in Fryeburg, Maine. The oldest portion of this house, now a portion of the elongated ell attached to the main block, was built c. 1767 by Nathaniel Merrill, one of the early settlers of Fryeburg after its land was granted to Joseph Frye in 1762. It was sold in 1799 to James Osgood, the son of another early settler. Stephen and Mary (Osgood) Chase inherited this property in 1824, and moved the main block of the house across the street to its present location, and attached the older house to it. The exterior of this house was Federal in styling, although its interior is now Greek Revival in character.