Tshepo Motsepe is the current second lady of South Africa and the wife of Cyril Ramaphosa the Deputy President of South Africa and the deputy president of South African ruling party the ANC. Biography Tshepo Motsepe is a successful mining executive and one, of Africas self made female millionaires. Tshepo is also the sister of South Africas first black Billionaire Patrice Motsepe. Tshepo is the second wife of Cyril Ramaphosa and the couple have no children. Tshepo is a Tswana.