Tuskegee (also spelled Toskegee, Taskigi, and similar variations) was an Overhill Cherokee town located along the Little Tennessee River in what is now Monroe County, Tennessee, United States. The town developed in the late 1750s alongside Fort Loudoun, and was inhabited until the late 1770s, when it was evacuated and probably burned during the Cherokee–American wars. Tuskegee is best known as the birthplace of the Cherokee craftsman Sequoyah. Now flooded by Tellico Lake, the Tuskegee site was investigated by archaeologists prior to inundation in the 1970s.