Mission Santa along with the Presidio San Luis de las Amarillas, later renamed Presidio of San Sabá, in what is now Menard County. Located along the San Saba River, the mission was intended to convert members of the Lipan Apache tribe. Although no Apache ever resided at the mission, its existence convinced the Comanche that the Spanish had allied with the Comanche's mortal enemy. In 1758 the mission was destroyed by 2,000 warriors from the Comanche, Tonkawa, Yojuane, Bidai and Hasinai tribes. It was the only mission in Texas to be completely destroyed by Native Americans. The Indians did not attack the nearby presidio.