State Route 554 (SR 554) is an east–west state highway located in the southeastern corner of Ohio, a U.S. state. The western terminus of State Route 554 is at State Route 325 about 1 mile (1.6 km) north of Rio Grande, and just 1 block north of the State Route 325 interchange off of U.S. Route 35. Its eastern terminus is at a signalized intersection with State Route 7 in Cheshire a mere two blocks west of the Ohio River.