Atypical chronic myeloid leukemia
Atypical chronic myeloid leukemia (aCML) is a type of leukemia. It is a heterogeneous disorder belonging to the group of myelodysplastic/myeloproliferative (MDS/MPN) syndromes. In aCML many clinical features (splenomegaly, myeloid predominance in the bone marrow with some dysplastic features but without a differentiation block) and laboratory abnormalities (myeloid proliferation, low leukocyte alkaline phosphatase values) suggest the diagnosis of chronic myelogenous leukemia (CML). However the lack of the pathognomonic Philadelphia chromosome and of the resulting BCR-ABL1 fusion point to a different pathogenetic process. Since no specific recurrent genomic or karyotypic abnormalities have been identified in aCML, the molecular pathogenesis of this disease has remained elusive and the outco
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Atypical chronic myeloid leukemia
Atypical chronic myeloid leukemia (aCML) is a type of leukemia. It is a heterogeneous disorder belonging to the group of myelodysplastic/myeloproliferative (MDS/MPN) syndromes. In aCML many clinical features (splenomegaly, myeloid predominance in the bone marrow with some dysplastic features but without a differentiation block) and laboratory abnormalities (myeloid proliferation, low leukocyte alkaline phosphatase values) suggest the diagnosis of chronic myelogenous leukemia (CML). However the lack of the pathognomonic Philadelphia chromosome and of the resulting BCR-ABL1 fusion point to a different pathogenetic process. Since no specific recurrent genomic or karyotypic abnormalities have been identified in aCML, the molecular pathogenesis of this disease has remained elusive and the outco
has abstract
Atypical chronic myeloid leuke ...... ellular levels of the protein.
@en
非定型慢性骨髄性白血病(ひていけいまんせいこつずいせいはっけ ...... icalは小文字、CMLは大文字で表記するのが一般的である。
@ja
Wikipage page ID
38,813,055
Wikipage revision ID
621,561,374
subject
hypernym
type
comment
Atypical chronic myeloid leuke ...... remained elusive and the outco
@en
非定型慢性骨髄性白血病(ひていけいまんせいこつずいせいはっけ ...... icalは小文字、CMLは大文字で表記するのが一般的である。
@ja
label
Atypical chronic myeloid leukemia
@en
非定型慢性骨髄性白血病
@ja