"Check My Brain" is a song by the American rock band Alice in Chains, featured on their fourth studio album Black Gives Way to Blue (2009). It was released as the second single from the album on August 17, 2009. The single topped the Billboard Hot Mainstream Rock Tracks and Billboard Rock Songs charts in September 2009. This was the first time an Alice in Chains song would hit #1 on the Hot Mainstream Rock Tracks chart since their 1994 single "No Excuses". "Check My Brain" received a nomination for "Best Hard Rock Performance" at the 52nd Grammy Awards. It was also their first #1 on the Alternative Songs chart.