D'Youville Academy is a historic school building and nunnery in Plattsburgh in Clinton County, New York. It was built about 1878 and is a  2 1⁄2-story, cruciform plan brick structure on a raised stone foundation. The facade features a rounded 2-story bay, a five-gable roof dormer, and Mansard roof. The Academy was founded in 1860 and operated by the Gray Nuns of Ottawa, founded by Saint Marie-Marguerite d'Youville (1701-1771). The Academy has since been folded into the Seton Catholic Central High School, and the building has since been converted into apartments.