D-amino acid oxidase activator
D-amino acid oxidase activator (DAOA, also known as G72) is a protein enriched in various parts of brain, spinal cord, and testis. DAOA is thought to interact with D-amino acid oxidase, a peroxisomal enzyme, and its gene was associated with schizophrenia in a number of studies. In separate studies it has been shown to confer susceptibility to bipolar disorder. Therefore, it has been important in researching whether the Kraepelinian dichotomy is genuine. The gene itself was discovered during an investigation of chromosomal 13q22-q34 region, which was previously linked to schizophrenia. G72 is transcribed into several proteins due to alternative splicing; the longest protein is called LG72 and consists of 153 amino acids. Although the protein was initially found to interact with DAO in yeast
Wikipage redirect
primaryTopic
D-amino acid oxidase activator
D-amino acid oxidase activator (DAOA, also known as G72) is a protein enriched in various parts of brain, spinal cord, and testis. DAOA is thought to interact with D-amino acid oxidase, a peroxisomal enzyme, and its gene was associated with schizophrenia in a number of studies. In separate studies it has been shown to confer susceptibility to bipolar disorder. Therefore, it has been important in researching whether the Kraepelinian dichotomy is genuine. The gene itself was discovered during an investigation of chromosomal 13q22-q34 region, which was previously linked to schizophrenia. G72 is transcribed into several proteins due to alternative splicing; the longest protein is called LG72 and consists of 153 amino acids. Although the protein was initially found to interact with DAO in yeast
has abstract
D-amino acid oxidase activator ...... iomarker for schizophrenia.[5]
@en
Активатор оксидазы D-аминокисл ...... кой депрессией и тревожностью.
@ru
chromosome
EntrezGene
HGNCid
OMIM id
RefSeq
Symbol
UniProt
Link from a Wikipage to an external page
Wikipage page ID
12,990,634
Wikipage revision ID
741,147,663
comment
D-amino acid oxidase activator ...... to interact with DAO in yeast
@en
Активатор оксидазы D-аминокисл ...... кой депрессией и тревожностью.
@ru
label
D-amino acid oxidase activator
@en
G72
@ru
wasDerivedFrom
isPrimaryTopicOf
name
D-amino acid oxidase activator
@en