Brian Shaffer (born February 25, 1979) was a medical student at The Ohio State University. On the night of March 31, 2006, he went out with friends to celebrate the beginning of spring break; later he was separated from them and they assumed he had gone home. However, a security camera near the entrance to a bar recorded him briefly talking to two women just before 2 a.m., April 1, and then apparently re-entering the bar. He has not been seen or heard from since. The case has received national media attention.