The 100,600-acre (407 km2) Eagletail Mountains Wilderness is part of the Eagletail Mountains of central-west Arizona, about 65 mi west of Phoenix. The wilderness is of moderate size, with the Eagletail Mountains forming its northeast perimeter, and the much shorter Cemetery Ridge section, forming its southwest border. The wilderness covers nearly all of the Eagletail Mountains and the plains on its southwest. The wilderness lies at the southeast of the Ranegras Plain, the headwater region of Bouse Wash, and lies adjacent to the northwest border of the extensive Gila Bend Mountains, the mountain range causing the great Gila Bend excursion of the Gila River, in Arizona.