Glutamate decarboxylase
Glutamate decarboxylase or glutamic acid decarboxylase (GAD) is an enzyme that catalyzes the decarboxylation of glutamate to GABA and CO2. GAD uses PLP as a cofactor. The reaction proceeds as follows: HOOC-CH2-CH2-CH(NH2)-COOH → CO2 + HOOC-CH2-CH2-CH2NH2 In mammals, GAD exists in two isoforms encoded by two different genes - GAD1 and GAD2. These isoforms are GAD67 and GAD65 with molecular weights of 67 and 65 kDa, respectively. GAD1 and GAD2 are expressed in the brain where GABA is used as a neurotransmitter, GAD2 is also expressed in the pancreas.
Anti-GAD antibodiesAnti-GAD antibodyEC 4.1.1.15GAD-44GAD-65GAD-67GAD25GAD44GAD65GAD65 antibodiesGAD67GAD67 antibodiesGAD 25GAD 44GAD 65GAD 67GAD antibodiesGAD antibodyGAD autoantibodiesGAD autoantibodyGlutamate decarboxylate-1Glutamic acid decarboxylaseL-Glutamic acid decarboxylaseL-glutamate 1-carboxy-lyase (4-aminobutanoate-forming)L-glutamic acid decarboxylase
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Glutamate decarboxylase
Glutamate decarboxylase or glutamic acid decarboxylase (GAD) is an enzyme that catalyzes the decarboxylation of glutamate to GABA and CO2. GAD uses PLP as a cofactor. The reaction proceeds as follows: HOOC-CH2-CH2-CH(NH2)-COOH → CO2 + HOOC-CH2-CH2-CH2NH2 In mammals, GAD exists in two isoforms encoded by two different genes - GAD1 and GAD2. These isoforms are GAD67 and GAD65 with molecular weights of 67 and 65 kDa, respectively. GAD1 and GAD2 are expressed in the brain where GABA is used as a neurotransmitter, GAD2 is also expressed in the pancreas.
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Glutamat-Decarboxylase (GAD) h ...... hirnen bei Embryonen entdeckt.
@de
Glutamate decarboxylase or glu ...... by both, GAD44 - only by I-80.
@en
Glutamato descarboxilase ou de ...... bos, GAD44 - apenas pelo I-80.
@pt
La glutamate décarboxylase, ou ...... est codée uniquement par I-80.
@fr
Глутаматдекарбоксилаза (англ. ...... ракте и обонятельной луковице.
@ru
グルタミン酸デカルボキシラーゼ、グルタミン酸脱炭酸酵素(Gl ...... 働きにより、グルタミン酸はGABAと二酸化炭素に分解される。
@ja
谷氨酸脱羧酶(英语:Glutamate decarboxyl ...... D25与GAD44(胎儿;EGAD)被发现于发育中的大脑中。
@zh
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744,872,173
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GAD67 derived from
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Glutamat-Decarboxylase (GAD) h ...... lparese Typ 1 (CPSQ1), führen.
@de
Glutamate decarboxylase or glu ...... lso expressed in the pancreas.
@en
Glutamato descarboxilase ou de ...... bos, GAD44 - apenas pelo I-80.
@pt
La glutamate décarboxylase, ou ...... est codée uniquement par I-80.
@fr
Глутаматдекарбоксилаза (англ. ...... AD является пиридоксальфосфат.
@ru
グルタミン酸デカルボキシラーゼ、グルタミン酸脱炭酸酵素(Gl ...... 働きにより、グルタミン酸はGABAと二酸化炭素に分解される。
@ja
谷氨酸脱羧酶(英语:Glutamate decarboxyl ...... D25与GAD44(胎儿;EGAD)被发现于发育中的大脑中。
@zh
label
Glutamat-Decarboxylase
@de
Glutamate decarboxylase
@en
Glutamate décarboxylase
@fr
Glutamato descarboxilase
@pt
Глутаматдекарбоксилаза
@ru
グルタミン酸デカルボキシラーゼ
@ja
谷氨酸脱羧酶
@zh
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glutamate decarboxylase
@en