The Historic Anderson House Hotel is a hotel and event venue in Wabasha, Minnesota, United States. The hotel opened in 1856 and was Minnesota's oldest continuously operating bed and breakfast inn west of the Mississippi River. Most of the furniture dates back to 1856 as well. The building was expanded in 1887. It was listed on the National Register of Historic Places as the Hurd House–Anderson Hotel in 1978 for having local significance in the theme of commerce. It was nominated for being a prominent and long-operating business originating in the years of Wabasha's rapid growth as a river and rail transportation hub. In 1982 it was also listed as a contributing property to the Wabasha Commercial Historic District.